Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537218 | 0.72 | HTR1A (0.39) | POLBHTR1FHTR1AHTR1BHTR1D | |
| SCHEMBL13537571 | 0.69 | HTR1A (0.63) | HTR1FHTR1AHTR1BHTR1DDRD2 | |
| SCHEMBL13537477 | 0.69 | HTR1B (0.39) | POLBHTR1FHTR1AHTR1BHTR1D | |
| SCHEMBL13537308 | 0.68 | OPRM1 (0.47) | HTR1FHTR1AHTR1BHTR1DPIM1 | |
| SCHEMBL13537478 | 0.68 | OPRM1 (0.47) | HTR1FHTR1AHTR1BHTR1D | |
| SCHEMBL13537396 | 0.67 | HTR1A (0.51) | HTR1FHTR1AHTR1BHTR1DDRD2 | |
| SCHEMBL13537597 | 0.66 | HTR1A (0.52) | HTR1FHTR1AHTR1BHTR1DDRD2 | |
| SCHEMBL13537498 | 0.65 | HTR1F (0.50) | HTR1FHTR1AHTR1BHTR1D | |
| SCHEMBL13537238 | 0.65 | HTR1F (0.62) | HTR1FHTR1AHTR1BHTR1D | |
| SCHEMBL15837036 | 0.64 | OPRM1 (0.40) | POLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |