Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.49 |
| ▸ | PIM1 | P11309 | 5/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425656 | 0.94 | GPR119 (0.49) | GPR119PIM1PIM2PIM3NR1H4 | |
| SCHEMBL2425657 | 0.94 | GPR119 (0.49) | GPR119PIM1PIM2PIM3NR1H4 | |
| SCHEMBL12282967 | 0.87 | GPR119 (0.51) | GPR119PIM1PIM2PIM3NR1H4 | |
| SCHEMBL13537792 | 0.85 | PIM1 (0.48) | GPR119PIM1PIM2PIM3NR1H4 | |
| SCHEMBL2428104 | 0.84 | PIM1 (0.66) | GPR119PIM1PIM2PIM3GSK3B | |
| SCHEMBL2424864 | 0.84 | PIM1 (0.66) | GPR119PIM1PIM2PIM3GSK3B | |
| SCHEMBL2426618 | 0.83 | PIM1 (0.45) | GPR119PIM1PIM2PIM3NR1H4 | |
| SCHEMBL2426616 | 0.83 | PIM1 (0.45) | GPR119PIM1PIM2PIM3NR1H4 | |
| SCHEMBL13537641 | 0.83 | PIM1 (0.63) | PIM1PIM2PIM3NR1H4PTPN1 | |
| SCHEMBL2428210 | 0.81 | PIM2 (0.61) | GPR119PIM1PIM2PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001169-A2 | CHEMICAL COMPOUNDS 251 | ASTRAZENECA AB (SE) | 2010-01-07 | — | — | WO | disclosed |