Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.78 |
| ▸ | ALPL | P05186 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ACR | P10323 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415732 | 0.87 | ALPL (1.00) | KDM4EALPLMAPTNPC1RAB9A | |
| SCHEMBL1416809 | 0.82 | MAPT (1.00) | KDM4EALPLMAPTNPC1RAB9A | |
| SCHEMBL13541923 | 0.82 | ALPL (0.70) | KDM4EALPLMAPTNPC1RAB9A | |
| SCHEMBL13971739 | 0.78 | MAPT (0.62) | KDM4EALPLMAPTNPC1RAB9A | |
| SCHEMBL14138506 | 0.75 | KDM4E (0.62) | KDM4EALPLMAPTNPC1RAB9A | |
| SCHEMBL13539274 | 0.75 | ALPL (0.77) | ALPLMAPTRAB9ALMNAMEN1 | |
| SCHEMBL13539269 | 0.74 | ALPL (0.73) | ALPLMAPTNPC1RAB9ALMNA | |
| SCHEMBL13539275 | 0.74 | ALPL (0.76) | ALPLMAPTNPC1RAB9ALMNA | |
| SCHEMBL19533624 | 0.74 | ALPL (0.47) | KDM4EALPLMAPTNPC1RAB9A | |
| SCHEMBL13175674 | 0.73 | ALPL (0.54) | KDM4EALPLMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016313-A1 | INTESTINAL ALKALINE PHOSPHATASE MODULATORS AND USES THEREOF | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016313-A1 | INTESTINAL ALKALINE PHOSPHATASE MODULATORS AND USES THEREOF | ALPI, SI, FABP2 | KDM4E 2989/4885ALPL 5/4885MAPT 4675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.