Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 5/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 7/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345920 | 0.94 | TYMS (0.57) | TYMSFGFR1SOAT1BCL2BCL2L1 | |
| SCHEMBL13829100 | 0.94 | TYMS (0.57) | TYMSFGFR1SOAT1BCL2BCL2L1 | |
| SCHEMBL17617816 | 0.91 | TYMS (0.62) | TYMSFGFR1SOAT1BCL2BCL2L1 | |
| SCHEMBL6516581 | 0.82 | TYMS (0.59) | TYMSFGFR1S100A4BCL2MEN1 | |
| SCHEMBL13829366 | 0.82 | KMT2A (0.50) | TYMSFGFR1SOAT1S100A4PTGS2 | |
| SCHEMBL13829210 | 0.80 | TYMS (0.60) | TYMSFGFR1BCL2PTGS2MEN1 | |
| SCHEMBL13829269 | 0.79 | TYMS (0.59) | TYMSFGFR1BCL2MEN1USP2 | |
| SCHEMBL13829120 | 0.78 | POLB (0.48) | TYMSFGFR1SOAT1PTGS2MEN1 | |
| SCHEMBL9450619 | 0.77 | KDM4E (0.50) | TYMSMEN1USP2POLBMAPT | |
| SCHEMBL12133954 | 0.76 | POLB (0.55) | FGFR1MEN1RGS12USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524914-B1 | SULFONIC ACID DERIVATIVE COMPOUND AND NAPHTHALIC ACID DERIVATIVE COMPOUND | ADEKA CORP (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-9518964-B2 | Method for identifying electrophiles and nucleophiles in a sample | EICHEN YOAV (IL) | 2016-12-13 | — | — | US | disclosed |
| US-9518964-B2 | Method for identifying electrophiles and nucleophiles in a sample | EICHEN YOAV (IL) | 2016-12-13 | — | — | US | disclosed |
| US-9518964-B2 | Method for identifying electrophiles and nucleophiles in a sample | EICHEN YOAV (IL) | 2016-12-13 | — | — | US | disclosed |
| US-8680268-B2 | Sulfonic acid derivative compound and novel naphthalic acid derivative compound | ADEKA CORPORATION (JP) | 2014-03-25 | — | — | US | disclosed |
| US-8680268-B2 | Sulfonic acid derivative compound and novel naphthalic acid derivative compound | ADEKA CORPORATION (JP) | 2014-03-25 | — | — | US | disclosed |
| EP-2524914-A1 | NOVEL SULFONIC ACID DERIVATIVE COMPOUND AND NOVEL NAPHTHALIC ACID DERIVATIVE COMPOUND | Adeka Corporation (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120289697-A1 | NOVEL SULFONIC ACID DERIVATIVE COMPOUND AND NOVEL NAPHTHALIC ACID DERIVATIVE COMPOUND | ADEKA CORPORATION (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20120289697-A1 | NOVEL SULFONIC ACID DERIVATIVE COMPOUND AND NOVEL NAPHTHALIC ACID DERIVATIVE COMPOUND | ADEKA CORPORATION (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| EP-2085766-A2 | Method for identifying electrophiles and nucleophiles in a sample | Technion Research and Development Foundation, Ltd. (IL) | 2009-08-05 | — | — | EP | disclosed |
| EP-2085766-A2 | Method for identifying electrophiles and nucleophiles in a sample | Technion Research and Development Foundation, Ltd. (IL) | 2009-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289697-A1 | NOVEL SULFONIC ACID DERIVATIVE COMPOUND AND NOVEL NAPHTHALIC ACID DERIVATIVE COMPOUND | TPD52L2, TST, SULT1A1 | TYMS 2935/4885FGFR1 119/4885SOAT1 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.