Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 9/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345920 | 1.00 | TYMS (0.57) | TYMSSOAT1FGFR1PTGS2P4HB | |
| SCHEMBL1354118 | 0.94 | TYMS (0.60) | TYMSSOAT1FGFR1PTGS2BCL2 | |
| SCHEMBL17617816 | 0.89 | TYMS (0.62) | TYMSSOAT1FGFR1BCL2BCL2L1 | |
| SCHEMBL13829120 | 0.83 | POLB (0.48) | TYMSSOAT1FGFR1PTGS2P4HB | |
| SCHEMBL6516581 | 0.80 | TYMS (0.59) | TYMSFGFR1BCL2 | |
| SCHEMBL28663739 | 0.79 | POLB (0.56) | TYMSSOAT1FGFR1 | |
| SCHEMBL11343907 | 0.78 | MEN1 (0.49) | TYMSFGFR1 | |
| SCHEMBL13829210 | 0.78 | TYMS (0.60) | TYMSFGFR1PTGS2BCL2 | |
| SCHEMBL18957987 | 0.78 | MAPT (0.41) | TYMSSOAT1FGFR1PTGS2 | |
| SCHEMBL13829366 | 0.77 | KMT2A (0.50) | TYMSSOAT1FGFR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524914-B1 | SULFONIC ACID DERIVATIVE COMPOUND AND NAPHTHALIC ACID DERIVATIVE COMPOUND | ADEKA CORP (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-8680268-B2 | Sulfonic acid derivative compound and novel naphthalic acid derivative compound | ADEKA CORPORATION (JP) | 2014-03-25 | — | — | US | disclosed |
| US-8680268-B2 | Sulfonic acid derivative compound and novel naphthalic acid derivative compound | ADEKA CORPORATION (JP) | 2014-03-25 | — | — | US | disclosed |
| EP-2524914-A1 | NOVEL SULFONIC ACID DERIVATIVE COMPOUND AND NOVEL NAPHTHALIC ACID DERIVATIVE COMPOUND | Adeka Corporation (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120289697-A1 | NOVEL SULFONIC ACID DERIVATIVE COMPOUND AND NOVEL NAPHTHALIC ACID DERIVATIVE COMPOUND | ADEKA CORPORATION (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20120289697-A1 | NOVEL SULFONIC ACID DERIVATIVE COMPOUND AND NOVEL NAPHTHALIC ACID DERIVATIVE COMPOUND | ADEKA CORPORATION (JP) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289697-A1 | NOVEL SULFONIC ACID DERIVATIVE COMPOUND AND NOVEL NAPHTHALIC ACID DERIVATIVE COMPOUND | TPD52L2, TST, SULT1A1 | TYMS 2935/4885SOAT1 2427/4885FGFR1 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.