Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10998848 | 0.98 | ACHE (0.47) | ACHECHRM5ADRA2CCHRM2CHRM4 | |
| SCHEMBL14828674 | 0.96 | CHRM5 (0.52) | ACHECHRM5ADRA2CCHRM2CHRM4 | |
| SCHEMBL4966539 | 0.93 | ACHE (0.42) | ACHECHRM5ADRA2CHRH3 | |
| SCHEMBL4966546 | 0.93 | ACHE (0.42) | ACHECHRM5ADRA2CHRH3 | |
| SCHEMBL1787100 | 0.91 | HRH3 (0.42) | ACHEHRH3 | |
| SCHEMBL22852502 | 0.91 | HRH3 (0.42) | ACHEHRH3 | |
| SCHEMBL16254938 | 0.89 | ALDH1A1 (0.44) | ACHECHRM5ADRA2CCHRM2HRH3 | |
| SCHEMBL16480437 | 0.82 | KCNH2 (0.44) | HRH3GBA1 | |
| SCHEMBL5504656 | 0.82 | GBA1 (0.44) | HRH3GBA1 | |
| SCHEMBL5504654 | 0.82 | HRH3 (0.39) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918340-B1 | LIGAND COMPOUND, CATALYST SYSTEM FOR OLIGOMERIZING OLEFIN, AND METHOD FOR OLIGOMERIZING OLEFIN USING SAME | LG CHEMICAL LTD (KR) | 2017-03-15 | — | — | EP | disclosed |
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-7649011-B2 | Active against cancer proliferation, growth, and metastasis; such as 3,4,5-trimethoxy-n-(2-methyl-3-phenyl-allyl)-n-[2-(1-methyl-pyrrolidin-2-yl)-thyl]-benzamide; side effect reduction | CHEMOCENTRYX, INC. (US) | 2010-01-19 | — | — | US | disclosed |