Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13525433 | 0.86 | KMT2A (0.43) | SLC7A5LTA4HKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL855512 | 0.83 | SLC7A5 (0.44) | SLC7A5LTA4HSYKKMT2ASMN1; SMN2 | |
| SCHEMBL28796517 | 0.81 | ACHE (0.43) | SLC7A5LTA4HSYKKMT2AMEN1 | |
| SCHEMBL27847543 | 0.81 | SLC7A5 (0.45) | SLC7A5LTA4HSYKKMT2ASMN1; SMN2 | |
| SCHEMBL27559984 | 0.79 | SLC7A5 (0.43) | SLC7A5LTA4H | |
| SCHEMBL8909021 | 0.78 | ADRB1 (0.46) | SLC7A5 | |
| SCHEMBL13546195 | 0.77 | CFD (0.43) | CFDF11TPSB2 | |
| SCHEMBL13546193 | 0.77 | TSHR (0.35) | KMT2ASMN1; SMN2CFDF11TPSB2 | |
| SCHEMBL3307226 | 0.77 | MEN1 (0.40) | SLC7A5LTA4HSYKKMT2AMEN1 | |
| SCHEMBL27881041 | 0.76 | SLC7A5 (0.44) | SLC7A5LTA4HSYKKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645748-B2 | include a phosphate linker, at least one nitrate group that releases nitric oxide (NO), and a sterol or stanol group; useful for treating atherosclerosis, hypercholesterolemia, hyperlipidemia, hypertension, thrombosis, Type II diabetes, dementia, Alzheimer's disease and aging | FORBES MEDI-TECH INC. (CA) | 2010-01-12 | — | — | US | disclosed |