Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535964 | 0.84 | — | — | |
| SCHEMBL11982081 | 0.74 | RAPGEF4 (0.36) | RAPGEF4 | |
| SCHEMBL13798732 | 0.73 | ALDH1A1 (0.58) | — | |
| SCHEMBL19446422 | 0.73 | SOS1 (0.31) | — | |
| SCHEMBL13798734 | 0.73 | CA1 (0.58) | — | |
| SCHEMBL13899602 | 0.71 | CYP3A4 (0.33) | — | |
| SCHEMBL1551822 | 0.69 | RAPGEF4 (0.59) | RAPGEF4 | |
| SCHEMBL18950483 | 0.69 | ALDH1A1 (0.53) | RAPGEF4TUBB1 | |
| SCHEMBL28951 | 0.69 | RAPGEF4 (0.59) | RAPGEF4 | |
| SCHEMBL14041669 | 0.69 | ACHE (0.40) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089384-B1 | 2-(PIPERIDIN-4-YL)-4-PHENOXY-OR PHENYLAMINO-PYRIMIDINE DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2015-08-05 | — | — | EP | disclosed |
| WO-2013003586-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-03 | — | — | WO | disclosed |
| US-7642277-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-05 | — | — | US | disclosed |
| EP-1787992-B1 | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-04-29 | — | — | EP | disclosed |
| EP-1626976-B1 | OLEFIN POLYMERIZATION CATALYST SYSTEM | EXXONMOBIL CHEM PATENTS INC (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1787992-A1 | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-05-23 | — | — | EP | disclosed |
| EP-1704149-B1 | TRIAZA-CYCLOPENTA[CD]INDENE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2007-03-07 | — | — | EP | disclosed |