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SCHEMBL13548691

SCHEMBL13548691

Cc1cc(Oc2ccccc2F)ccc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ HSPB1 P04792 4/20 0.55
▸ MEN1 O00255 3/20 0.49
▸ KMT2A Q03164 3/20 0.49
▸ POLB P06746 2/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ MAPT P10636 4/20 0.49
▸ PIN1 Q13526 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ NPC1 O15118 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ ATM Q13315 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ PARP10 Q53GL7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30764792 1.00 HSPB1 (0.55) HSPB1MEN1KMT2APOLBL3MBTL1
SCHEMBL16792426 0.89 MEN1 (0.47) HSPB1MEN1KMT2APOLBL3MBTL1
SCHEMBL4065173 0.89 HSPB1 (0.55) HSPB1MEN1KMT2APOLBMAPT
SCHEMBL2535336 0.87 HSD17B10 (0.53) MEN1KMT2APOLBL3MBTL1MAPT
SCHEMBL16814207 0.86 HSPB1 (0.42) HSPB1MEN1KMT2APOLBL3MBTL1
SCHEMBL13548683 0.84 L3MBTL1 (0.60) MEN1KMT2APOLBL3MBTL1MAPT
SCHEMBL18956866 0.83 MEN1 (0.49) MEN1KMT2APOLBL3MBTL1MAPT
SCHEMBL21617079 0.83 HSPB1 (0.55) HSPB1MEN1KMT2AL3MBTL1MAPT
SCHEMBL30073074 0.83 MEN1 (0.49) MEN1KMT2APOLBL3MBTL1MAPT
SCHEMBL28604761 0.83 L3MBTL1 (0.49) MEN1KMT2APOLBL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035348-A1 PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2026-02-05 — — US disclosed
US-12479802-B2 Phenyl-n-quinoline derivatives for treating a RNA virus infection ABIVAX (FR) 2025-11-25 — — US disclosed
US-20240308964-A1 PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2024-09-19 — — US disclosed
US-12084422-B2 Phenyl-n-quinoline derivatives for treating a RNA virus infection ABIVAX (FR) 2024-09-10 — — US disclosed
CN-112566899-B phenyl-N-quinoline derivatives for the treatment of RNA viral infections ABIVAX公司 2024-01-30 — — CN disclosed
US-20210309611-A1 PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-10-07 — — US disclosed
EP-3820852-A1 PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-05-19 — — EP disclosed
CN-112566899-A phenyl-N-quinoline derivatives for the treatment of RNA viral infections ABIVAX公司 2021-03-26 — — CN disclosed
WO-2020011810-A1 PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 — — WO disclosed
EP-3080099-B1 INHIBITORS OF BRUTON'S TYROSINE KINASE HOFFMANN LA ROCHE (CH) 2018-04-11 — — EP disclosed
US-9556150-B2 Inhibitors of bruton's tyrosine kinase HOFFMANN-LA ROCHE INC. (US) 2017-01-31 — — US disclosed
US-9556150-B2 Inhibitors of bruton's tyrosine kinase HOFFMANN-LA ROCHE INC. (US) 2017-01-31 — — US disclosed
US-20160311801-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE CHUGAI PHARMACEUTICAL CO. (JP) 2016-10-27 — — US disclosed
US-20160311801-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE CHUGAI PHARMACEUTICAL CO. (JP) 2016-10-27 — — US disclosed
EP-3080099-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE F. Hoffmann-La Roche AG (CH) 2016-10-19 — — EP disclosed
WO-2015086642-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE F. HOFFMANN-LA ROCHE AG (CH) 2015-06-18 — — WO disclosed
US-7642278-B2 Nitrogen compounds such as 3-(5-morpholin-4-yl-1H-benz-imidazol-2-yl)-1H-indazole and/or isomers, used as immunology modulators, antidiabetic agents, antiogenesis inhibitors or for prophylaxis of Alzheimer's disease NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2010-01-05 — — US disclosed
US-7642278-B2 Nitrogen compounds such as 3-(5-morpholin-4-yl-1H-benz-imidazol-2-yl)-1H-indazole and/or isomers, used as immunology modulators, antidiabetic agents, antiogenesis inhibitors or for prophylaxis of Alzheimer's disease NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2010-01-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308964-A1 PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ORC3, NSUN3, POLR2H HSPB1 4534/4885MEN1 4277/4885KMT2A 4178/4885
US-12084422-B2 Phenyl-n-quinoline derivatives for treating a RNA virus infection ORC3, NSUN3, POLR2H HSPB1 4534/4885MEN1 4277/4885KMT2A 4178/4885
US-20260035348-A1 PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION SARS1, NDUFC2, CLIC1 HSPB1 4421/4885MEN1 3696/4885KMT2A 2282/4885
US-20160311801-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE BTK, SYK, LYN HSPB1 947/4885MEN1 3945/4885KMT2A 2113/4885
US-12479802-B2 Phenyl-n-quinoline derivatives for treating a RNA virus infection ORC3, NSUN3, POLR2H HSPB1 4534/4885MEN1 4277/4885KMT2A 4178/4885
US-20210309611-A1 PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ORC3, NSUN3, POLR2H HSPB1 4534/4885MEN1 4277/4885KMT2A 4178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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