Sugi Predict

Sugi Predict / Compounds / SCHEMBL135501

SCHEMBL135501

SCHEMBL135501

[Li]c1ccc([Li])c2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.39
▸ HSD17B10 Q99714 5/20 0.39
▸ CYP2A6 P11509 3/20 0.39
▸ TSHR P16473 2/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ CYP1A2 P05177 5/20 0.37
▸ IDO1 P14902 1/20 0.37
▸ GPR3 P46089 4/20 0.35
▸ HPRT1 P00492 1/20 0.35
▸ KDM4E B2RXH2 2/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HPGD P15428 2/20 0.32
▸ HIF1A Q16665 1/20 0.32
▸ CYP1B1 Q16678 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ ALOX12 P18054 1/20 0.31
▸ CYP3A4 P08684 1/20 0.30
▸ KEAP1 Q14145 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658213 1.00 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL3925445 0.85 CYP1A2 (0.37) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL11659442 0.83 RXFP1 (0.39) ALDH1A1CYP1A2KDM4ESMN1; SMN2HPGD
SCHEMBL4471056 0.77 IDO1 (0.57) ALDH1A1HSD17B10CYP1A2IDO1KDM4E
SCHEMBL2159006 0.76 — —
SCHEMBL238050 0.74 ALDH1A1 (0.53) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL29585978 0.74 ALDH1A1 (0.53) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL3079050 0.73 HPRT1 (0.67) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL2139458 0.72 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Methane SCHEMBL5212093 0.72 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108395544-B Large-scale preparation method of triazine skeleton covalent polymer 中国科学院上海高等研究院 2021-03-16 — — CN claimed
US-7279527-B2 Method of converting anionic living end to protected free radical living end and applications thereof BRIDGESTONE CORPORATION (JP) 2007-10-09 — — US claimed
US-20060241265-A1 Method of converting anionic living end to protected free radical living end and applications thereof BRIDGESTONE CORPORATION (JP) 2006-10-26 — — US claimed
EP-0238784-B1 PROCESS AND SYSTEM FOR PREPARING RANDOM COPOLYMERS HAVING LOW VINYL CONTENTS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1993-03-17 — — EP claimed
EP-0258167-A2 Modifier for lithium catalysts THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-03-02 — — EP claimed
EP-0238784-A2 Process and system for preparing random copolymers having low vinyl contents THE FIRESTONE TIRE & RUBBER COMPANY (US) 1987-09-30 — — EP claimed
US-4696986-A 1,2,3- OR 1,2,4-TRIALKOXYBENZENE MODIFIERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-29 — — US claimed
US-4672097-A ANIONIC INITIATORS; SODIUM MAGNESIATE AND ORGANOLITHIUM COMPOUNDS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1987-06-09 — — US claimed
US-4537939-A ORGANOLITHIUM INITIATOR WITH A TRI-N-HETEROCYCLIC PHOSPHINE OXIDE MODIFIER THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-08-27 — — US claimed
US-4284741-A ORGANOLITHIUM ANIONIC POLYMERIZATION CATALYST, CYCLO-OCTATETRAENE OR -HEPTATRIENE PHILLIPS PETROLEUM COMPANY (US) 1981-08-18 — — US claimed
US-4111915-A LITHIUM ALKENOXIDES IN PREPARATION OF FUNCTIONAL LIQUID CONJUGATED DIENE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1978-09-05 — — US claimed
US-4046745-A CONJUGATED DIENE POLYMERS WITH HYDROXY FUNCTIONALITY PHILLIPS PETROLEUM COMPANY (US) 1977-09-06 — — US claimed
US-3993853-A HYDROXY FUNCTIONAL POLYMERS FROM LITHIUM SALTS OF HYDROXYALKYL CONJUGATED DIENES PHILLIPS PETROLEUM COMPANY (US) 1976-11-23 — — US claimed
US-12515174-B2 Articles including an isoporous membrane disposed on a porous substrate and methods of making the same SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-06 — — US disclosed
US-12509556-B2 Functionalized hydrogenated interpolymer with non-hydrogenated segment BRIDGESTONE CORPORATION (JP) 2025-12-30 — — US disclosed
US-12410274-B2 Anionic dispersion polymerization process to make random copolymer rubber BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 — — US disclosed
US-4091198-A Suppressing gel in the continuous solution polymerization of a conjugated diene with a monovinyl aromatic compound PHILLIPS PETROLEUM COMPANY (US) 1978-05-23 — — US disclosed
US-4046745-A CONJUGATED DIENE POLYMERS WITH HYDROXY FUNCTIONALITY PHILLIPS PETROLEUM COMPANY (US) 1977-09-06 — — US disclosed
US-3993853-A HYDROXY FUNCTIONAL POLYMERS FROM LITHIUM SALTS OF HYDROXYALKYL CONJUGATED DIENES PHILLIPS PETROLEUM COMPANY (US) 1976-11-23 — — US disclosed
US-3970607-A LITHIUM CATALYST THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509556-B2 Functionalized hydrogenated interpolymer with non-hydrogenated segment VCL, ILK, RIF1 ALDH1A1 3138/4885HSD17B10 3584/4885CYP2A6 4258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.