Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbon Dioxide SCHEMBL29620343 | 0.92 | HPRT1 (0.56) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| SCHEMBL238050 | 0.85 | ALDH1A1 (0.53) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| SCHEMBL29585978 | 0.85 | ALDH1A1 (0.53) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| Methane SCHEMBL5212093 | 0.82 | ALDH1A1 (0.50) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| Chrysene SCHEMBL384031 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| Chrysene SCHEMBL9786466 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| SCHEMBL29640482 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| SCHEMBL31177955 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| SCHEMBL25510 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 | |
| Chrysene SCHEMBL27115 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112239424-B | Preparation method of aristolochia alkaloids and intermediate thereof | 温州医科大学 | 2022-06-21 | — | — | CN | disclosed |
| US-7794632-B2 | Process for the preparation of pure aryllithium compounds and their use | CHEMETALL GMBH (DE) | 2010-09-14 | — | — | US | disclosed |
| EP-1547993-A4 | PROCESS FOR PREPARATION OF SPIROFLUORENOLS | TOKUYAMA CORP (JP) | 2007-11-07 | — | — | EP | disclosed |
| US-20070187847-A1 | Process for the preparation of pure aryllithium compounds and their use | EMMEL UTE | 2007-08-16 | — | — | US | disclosed |
| CN-1307140-C | Process for preparing spirofluorenols | TOKUYAMA CORP (JP) | 2007-03-28 | — | — | CN | disclosed |
| CN-1307140-C | Process for preparing spirofluorenols | TOKUYAMA CORP (JP) | 2007-03-28 | — | — | CN | disclosed |
| US-7087798-B2 | Process for preparation of spirofluorenols | TOKUYAMA CORPORATION (JP) | 2006-08-08 | — | — | US | disclosed |
| US-7087798-B2 | Process for preparation of spirofluorenols | TOKUYAMA CORPORATION (JP) | 2006-08-08 | — | — | US | disclosed |
| EP-1295887-B1 | Preparation of pure aryl lithium compounds | CHEMETALL GMBH (DE) | 2006-08-02 | — | — | EP | disclosed |
| US-20060091569-A1 | Process for the preparation of pure aryllithium compounds and their use | EMMEL UTE | 2006-05-04 | — | — | US | disclosed |
| US-20060025636-A1 | Process for preparation of spirofluorenols | TOKUYAMA CORPORATION (JP) | 2006-02-02 | — | — | US | disclosed |
| US-20060025636-A1 | Process for preparation of spirofluorenols | TOKUYAMA CORPORATION (JP) | 2006-02-02 | — | — | US | disclosed |
| CN-1694860-A | Process for preparing spirofluorenols | TOKUYAMA CORP (JP) | 2005-11-09 | — | — | CN | disclosed |
| CN-1694860-A | Process for preparing spirofluorenols | TOKUYAMA CORP (JP) | 2005-11-09 | — | — | CN | disclosed |
| EP-1547993-A1 | PROCESS FOR PREPARATION OF SPIROFLUORENOLS | Tokuyama Corporation (JP) | 2005-06-29 | — | — | EP | disclosed |
| EP-1547993-A1 | PROCESS FOR PREPARATION OF SPIROFLUORENOLS | Tokuyama Corporation (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004022514-A1 | PROCESS FOR PREPARATION OF SPIROFLUORENOLS | TOKUYAMA CORPORATION (JP) | 2004-03-18 | — | — | WO | disclosed |
| US-20030155665-A1 | Process for the preparation of pure aryllithium compounds and their use | CHEMETALL GMBH (DE) | 2003-08-21 | — | — | US | disclosed |
| EP-1295887-A1 | Preparation of pure aryl lithium compounds and their use | Chemetall GmbH (DE) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025636-A1 | Process for preparation of spirofluorenols | CYP2F1, DHCR7, HSD17B7 | HPRT1 4091/4885ALDH1A1 911/4885HSD17B10 312/4885 |
| US-20060091569-A1 | Process for the preparation of pure aryllithium compounds and their use | TYR, MLLT3, MLLT1 | HPRT1 316/4885ALDH1A1 3105/4885HSD17B10 3080/4885 |
| US-20070187847-A1 | Process for the preparation of pure aryllithium compounds and their use | TYR, MLLT3, MLLT1 | HPRT1 316/4885ALDH1A1 3105/4885HSD17B10 3080/4885 |
| US-20030155665-A1 | Process for the preparation of pure aryllithium compounds and their use | TYR, MLLT3, MLLT1 | HPRT1 316/4885ALDH1A1 3105/4885HSD17B10 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.