SCHEMBL1355401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1356145	0.86	ADORA2A (0.44)	KMT2AMAPTL3MBTL1ADORA2AADORA1
	SCHEMBL14810942	0.83	ADORA2A (0.50)	KMT2AMAPTL3MBTL1ADORA2AADORA1
	SCHEMBL31124459	0.83	ADORA2A (0.48)	KMT2AMAPTL3MBTL1ADORA2AADORA1
	SCHEMBL1356094	0.82	ADORA2A (0.47)	KMT2AMAPTL3MBTL1ADORA2AADORA1
	SCHEMBL1353828	0.78	ADORA2A (0.46)	KMT2AADORA2AADORA1TSHRPOLB
	SCHEMBL14812164	0.76	JAK3 (0.53)	ADORA2AADORA1
	SCHEMBL14812087	0.74	TSHR (0.48)	KMT2AMAPTL3MBTL1ADORA2AADORA1
	SCHEMBL1356280	0.73	NPBWR1 (0.45)	MAPTHPGDSMN1; SMN2ALDH1A1LMNA
	SCHEMBL17193676	0.69	ALDH1A1 (0.48)	MAPTL3MBTL1ADORA2AADORA1MGLL
	SCHEMBL29730634	0.69	ALDH1A1 (0.48)	MAPTL3MBTL1ADORA2AADORA1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.