⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997643 | 0.87 | — | — | |
| SCHEMBL30644028 | 0.84 | MEN1 (0.32) | — | |
| SCHEMBL5932857 | 0.79 | CA2 (0.37) | — | |
| SCHEMBL21547798 | 0.78 | ABCB11 (0.35) | — | |
| SCHEMBL12189452 | 0.75 | HPGD (0.32) | — | |
| SCHEMBL18902701 | 0.74 | MEN1 (0.37) | — | |
| SCHEMBL15984875 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL17243850 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL7901114 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL39815 | 0.74 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |
| US-20170267891-A1 | METHOD OF MANUFACTURING POLYMER COATED FERROMAGNETIC PARTICLES | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2017-09-21 | — | — | US | disclosed |
| WO-2017079867-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-05-18 | — | — | WO | disclosed |
| US-20160082102-A1 | BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS | UNIV YALE (US) | 2016-03-24 | — | — | US | disclosed |
| US-9202632-B2 | Double-center quaternary ammonium salt ion liquid, preparation method therefor and use thereof | OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2015-12-01 | — | — | US | disclosed |
| US-9181224-B2 | Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus | YALE UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| EP-2752861-A1 | DOUBLE-CENTER QUATERNARY AMMONIUM SALT ION LIQUID, PREPARATION METHOD THEREFOR AND USE THEREOF | Ocean's King Lighting Science&Technology Co., Ltd. (CN) | 2014-07-09 | — | — | EP | disclosed |
| US-20140158928-A1 | DOUBLE-CENTER QUATERNARY AMMONIUM SALT ION LIQUID, PREPARATION METHOD THEREFOR AND USE THEREOF | SHENZHEN OCEAN'S KING LIGHTING ENGINEERING CO.,LTD | 2014-06-12 | — | — | US | disclosed |
| US-8629104-B2 | G-CSF and water-soluble polymer conjugate | JIANGSU HENGRUI MEDICINE CO. LTD. (CN) | 2014-01-14 | — | — | US | disclosed |
| US-20130109623-A1 | G-CSF AND WATER-SOLUBLE POLYMER CONJUGATE | JIANGSU HENGRUI MEDICINE CO. LTD | 2013-05-02 | — | — | US | disclosed |
| US-20120269766-A1 | BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS | YALE UNIVERSITY (US) | 2012-10-25 | — | — | US | disclosed |