SCHEMBL7901114

SCHEMBL7901114

CNCCOCCOCCOC

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
RECQL P46063 1/20 0.37
CA2 P00918 1/20 0.34
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ABCB11 O95342 1/20 0.30
CYP3A4 P08684 1/20 0.30
ADRA2B P18089 1/20 0.30
OPRD1 P41143 1/20 0.30
SCN5A Q14524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16379700 1.00 KDM4E (0.37) KDM4ERECQLCA2HTR1DHTR1B
SCHEMBL16806579 1.00 KDM4E (0.37) KDM4ERECQLCA2HTR1DHTR1B
SCHEMBL27333126 1.00 KDM4E (0.37) KDM4ERECQLCA2HTR1DHTR1B
SCHEMBL39815 1.00 KDM4E (0.37) KDM4ERECQLCA2HTR1DHTR1B
SCHEMBL6935868 1.00
SCHEMBL19202513 1.00 KDM4E (0.37) KDM4ERECQLCA2HTR1DHTR1B
SCHEMBL15984875 1.00 KDM4E (0.37) KDM4ERECQLCA2HTR1DHTR1B
SCHEMBL17243850 1.00 KDM4E (0.37) KDM4ERECQLCA2HTR1DHTR1B
SCHEMBL21876827 1.00 KDM4E (0.37) KDM4ERECQLCA2HTR1DHTR1B
Bromide SCHEMBL23217987 0.97 KDM4E (0.36) KDM4ERECQLCA2HTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025105486-A1 ANTIBODY-PHOTOSENSITIVE SUBSTANCE CONJUGATE 第一三共株式会社 2025-05-22 WO disclosed
EP-4436972-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS RMW Cho Group Limited (HK) 2024-10-02 EP disclosed
EP-4395549-A1 COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL Oerth Bio LLC (US) 2024-07-10 EP disclosed
US-20230365577-A1 Photodynamic Therapy and Diagnosis RMW CHO GROUP LIMITED (HK) 2023-11-16 US disclosed
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-10-19 US disclosed
WO-2023094679-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS RMW CHO GROUP LIMITED (CN) 2023-06-01 WO disclosed
WO-2023094677-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS RMW CHO GROUP LIMITED (CN) 2023-06-01 WO disclosed
WO-2023081141-A1 THYMIDYLATE SYNTHASE INHIBITORS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-05-11 WO disclosed
US-20230104936-A1 TRPML MODULATORS CASMA THERAPEUTICS, INC. 2023-04-06 US disclosed
WO-2023034411-A1 COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL OERTH BIO LLC (US) 2023-03-09 WO disclosed
US-9878047-B2 Prodrugs of peptide epoxy ketone protease inhibitors ONYX THERAPEUTICS, INC. (US) 2018-01-30 US disclosed
US-20170247403-A1 TETRACYCLIC ANTHRAQUINONE DERIVATIVES TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) 2017-08-31 US disclosed
US-20170247403-A1 TETRACYCLIC ANTHRAQUINONE DERIVATIVES TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) 2017-08-31 US disclosed
WO-2017030814-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINS Arvinas, Inc. (US) 2017-02-23 WO disclosed
WO-2017011371-A1 MDM2-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE ARVINAS, INC (US) 2017-01-19 WO disclosed
US-9061069-B2 Use of constrained peptide mimic oligomers as vectorization agents CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-06-23 US disclosed
US-20140243322-A1 BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME COFERON, INC. (US) 2014-08-28 US disclosed
US-20120184480-A1 USE OF CONSTRAINED DIPEPTIDE AND TRIPEPTIDE MIMIC OLIGOMERS AS VECTORIZATION AGENTS UNIVERSITE DE MONTPELLIER I (FR) 2012-07-19 US disclosed
US-6187955-B1 A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS KAO CORPORATION (JP) 2001-02-13 US disclosed
US-5723133-A GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING KAO CORPORATION (JP) 1998-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140243322-A1 BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME BRDT, BRD2, BRD4 KDM4E 1492/4885RECQL 1712/4885CA2 3216/4885
US-20120184480-A1 USE OF CONSTRAINED DIPEPTIDE AND TRIPEPTIDE MIMIC OLIGOMERS AS VECTORIZATION AGENTS DNPEP, IAPP, VIP KDM4E 4771/4885RECQL 2423/4885CA2 3146/4885
US-20230104936-A1 TRPML MODULATORS TRPM2, TRPM4, TRPM5 KDM4E 2480/4885RECQL 3040/4885CA2 294/4885
US-20170247403-A1 TETRACYCLIC ANTHRAQUINONE DERIVATIVES ANTXR2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TBXA2R KDM4E 3461/4885RECQL 59/4885CA2 1291/4885
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, DDX21, SNRPE KDM4E 4176/4885RECQL 794/4885CA2 4173/4885
US-20230365577-A1 Photodynamic Therapy and Diagnosis PPOX, PPIF, ALAD KDM4E 4532/4885RECQL 1645/4885CA2 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.