⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10704335 | 0.98 | RAB9A (0.56) | — | |
| Hydrochloric Acid SCHEMBL28089121 | 0.98 | RAB9A (0.56) | — | |
| Propionic Acid SCHEMBL28285873 | 0.88 | RAB9A (0.51) | — | |
| Ethoxycarbonyl Group SCHEMBL28051789 | 0.83 | RAB9A (0.44) | — | |
| SCHEMBL3643530 | 0.83 | RAB9A (0.54) | — | |
| SCHEMBL4507702 | 0.80 | LMNA (0.53) | — | |
| SCHEMBL5216349 | 0.80 | EPHX2 (0.54) | — | |
| SCHEMBL20729480 | 0.79 | CYP2A6 (0.54) | — | |
| SCHEMBL215190 | 0.79 | LMNA (0.55) | — | |
| Pyridine SCHEMBL61964 | 0.78 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062756-B | Stenhouse donor-acceptor adducts of mevalonate activated furan and 3-pyridylethylamine and methods of synthesizing the same | 南京理工大学 | 2023-07-07 | — | — | CN | claimed |
| CN-112062756-A | Mannhouse donor-acceptor adduct of furan and 3-pyridine ethylamine activated by Merlox acid and synthetic method thereof | 南京理工大学 | 2020-12-11 | — | — | CN | claimed |
| US-9551018-B2 | Process for the preparation of optically active chiral amines | LONZA AG (CH) | 2017-01-24 | — | — | US | claimed |
| US-9394297-B2 | Amides as pim inhibitors | AMGEN INC. (US) | 2016-07-19 | — | — | US | claimed |
| US-20150329538-A1 | AMIDES AS PIM INHIBITORS | AMGEN INC. (US) | 2015-11-19 | — | — | US | claimed |
| US-20150284752-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | LONZA AG (CH) | 2015-10-08 | — | — | US | claimed |
| US-9074228-B2 | Process for the preparation of optically active chiral amines | LONZA AG (CH) | 2015-07-07 | — | — | US | claimed |
| EP-2202318-A1 | Process for the preparation of optically active chiral amines | Lonza AG (CH) | 2010-06-30 | — | — | EP | claimed |
| EP-1987152-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | LONZA AG (CH) | 2010-05-26 | — | — | EP | claimed |
| US-20090246837-A1 | Process for The Preparation of Optically Active Chiral Amines | LONZA AG (CH) | 2009-10-01 | — | — | US | claimed |
| EP-1987152-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | Lonza AG (CH) | 2008-11-05 | — | — | EP | claimed |
| EP-1897956-A1 | Process for preparation of optically active amines by optical resolution of racemic amines employing a bacterial omega-transaminase | Lonza AG (CH) | 2008-03-12 | — | — | EP | claimed |
| WO-2007093372-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CHIRAL AMINES | LONZA AG (CH) | 2007-08-23 | — | — | WO | claimed |
| EP-1818411-A1 | Process for the preparation of optically active chiral amines | Lonza AG (CH) | 2007-08-15 | — | — | EP | claimed |
| EP-1381607-B1 | NOVEL PYRIDINE- AND CYCLOHEXENYL-COMPRISING PYRROLOBENZODIAZEPINE-CARBOXAMIDES AND DERIVATIVES THEREOF; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | WYETH CORP (US) | 2005-10-26 | — | — | EP | claimed |
| EP-1568770-A2 | Pharmaceutical use of compounds which bind to a mammalian \"trace amine\" receptor | Oregon Health & Science University (US) | 2005-08-31 | — | — | EP | claimed |
| US-20040072187-A1 | Novel mammalian receptor genes and uses | OREGON HEALTH & SCIENCE UNIVERSITY | 2004-04-15 | — | — | US | claimed |
| EP-1319070-A2 | MAMMALIAN RECEPTOR GENES AND USES | Oregon Health & Science University (US) | 2003-06-18 | — | — | EP | claimed |
| WO-2002022801-A2 | MAMMALIAN RECEPTOR GENES AND USES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2002-03-21 | — | — | WO | claimed |
| US-4515708-A | BETA-PYRIDYLETHYLAMINE | EXXON RESEARCH & ENGINEERING CO. (US) | 1985-05-07 | — | — | US | claimed |