Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CD40 | P25942 | 1/20 | 0.47 |
| ▸ | CD40LG | P29965 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20746895 | 0.90 | MPL (0.56) | MPLALDH1A1HIF1AENPP2CYP1A2 | |
| SCHEMBL20306013 | 0.90 | ALDH1A1 (0.58) | MPLALDH1A1HIF1AENPP2CYP1A2 | |
| SCHEMBL9999809 | 0.86 | CYP1A2 (0.58) | MPLALDH1A1HIF1AENPP2CYP1A2 | |
| SCHEMBL18218255 | 0.85 | ALDH1A1 (0.56) | MPLALDH1A1HIF1AENPP2CYP1A2 | |
| SCHEMBL18218254 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HIF1AENPP2CYP1A2CYP2C9 | |
| SCHEMBL17515765 | 0.82 | PRMT3 (0.53) | MPLALDH1A1HIF1AENPP2CYP1A2 | |
| SCHEMBL19958091 | 0.82 | PRMT3 (0.53) | MPLALDH1A1HIF1AENPP2CYP1A2 | |
| SCHEMBL17540328 | 0.82 | PRMT3 (0.53) | MPLALDH1A1HIF1AENPP2CYP1A2 | |
| SCHEMBL17791867 | 0.82 | PRMT3 (0.64) | MPLALDH1A1HIF1AENPP2CYP1A2 | |
| SCHEMBL13763553 | 0.82 | ALDH1A1 (0.53) | MPLALDH1A1HIF1AENPP2CD40 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293695-B2 | Shading composition | BASF SE (DE) | 2012-10-23 | — | — | US | disclosed |