SCHEMBL17515765

SCHEMBL17515765

CN=Nc1ccc(N=Nc2c(S(=O)(=O)O)cc3cc(C)ccc3c2O)cc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PRMT3 O60678 1/20 0.53
▸ EP300 Q09472 1/20 0.53
▸ PRMT6 Q96LA8 1/20 0.53
▸ PRMT1 Q99873 1/20 0.53
▸ ENPP2 Q13822 10/20 0.52
▸ CYP1A2 P05177 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.50
▸ HIF1A Q16665 1/20 0.50
▸ CD40 P25942 1/20 0.49
▸ CD40LG P29965 1/20 0.49
▸ CA2 P00918 1/20 0.49
▸ CA3 P07451 1/20 0.49
▸ MPL P40238 1/20 0.41
▸ PHLPP2 Q6ZVD8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540328 1.00 PRMT3 (0.53) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL19958091 1.00 PRMT3 (0.53) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL9999809 0.94 CYP1A2 (0.58) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL17791867 0.90 PRMT3 (0.64) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL19958090 0.88 PHLPP2 (0.54) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL20306679 0.86 ENPP2 (0.54) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL20306013 0.85 ALDH1A1 (0.58) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL13631321 0.84 ENPP2 (0.54) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL13556980 0.82 MPL (0.61) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL22256277 0.81 PRMT3 (0.56) PRMT3EP300PRMT6PRMT1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160041321-A1 Achromatic Dye-Based Highly-Transmissive Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 — — US disclosed
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