SCHEMBL135570

SCHEMBL135570

CCCc1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.63
TSHR P16473 2/20 0.60
CNR2 P34972 8/20 0.59
NR1H2 P55055 3/20 0.47
NR1H3 Q13133 3/20 0.47
ESRRG P62508 1/20 0.47
NR3C1 P04150 1/20 0.46
CHRM2 P08172 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KCNH2 Q12809 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14283665 0.98 CYP2C19 (0.61) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL6676662 0.89 CYP2C19 (0.59) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL4407604 0.88 CYP2C19 (0.67) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL4400874 0.85 TSHR (0.78) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL379145 0.84 CYP2C19 (0.62) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL6680526 0.84 CYP2C19 (0.68) CYP2C19TSHRCNR2NR1H2NR1H3
Butane SCHEMBL28032421 0.84 TSHR (0.76) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL2960872 0.83 CYP2C19 (0.78) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL14283605 0.83 TSHR (0.75) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL7048164 0.82 CYP1A2 (0.51) CYP2C19TSHRCNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56150749-A None JP disclosed
CN-102799085-B Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, method of producing electrophotographic photosensitive member, and urea compound CANON KK 2014-12-03 CN disclosed
CN-103889961-A Substituted pyrazolyl-based carboxamide and urea derivatives bearing phenyl groups substituted by oxygen-containing groups as vanilloid receptor ligands GRUENENTHAL GMBH 2014-06-25 CN disclosed
CN-103242167-A Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH CO LTD 2013-08-14 CN disclosed
CN-102356356-B Electrophotographic photoconductor, production method of the same,image forming apparatus, and process cartridge RICOH CO LTD 2013-07-24 CN disclosed
CN-101833254-B Toner and two-component developer SHARP KK 2013-03-27 CN disclosed
CN-101907839-B Method of manufacturing resin-layer coated carrier, resin-layer coated carrier, developer, developing device, and image forming apparatus SHARP KK 2012-12-19 CN disclosed
CN-102799085-A Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, method of producing electrophotographic photosensitive member, and urea compound CANON KK 2012-11-28 CN disclosed
CN-101692156-B Method for manufacturing toner SHARP KK 2012-09-19 CN disclosed
CN-101482709-B Method for producing toner SHARP KK 2012-09-19 CN disclosed
US-20030206754-A1 Electrophotographic; multiple number of photoreceptors for multiple development colors including black, is constructed such that the photoreceptors satisfy a specific relation SHARP KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
CN-1453654-A Colour image forming apparatus SHARP KK (JP) 2003-11-05 CN disclosed
CN-1445618-A Colour image forming device SHARP KK (JP) 2003-10-01 CN disclosed
CN-1438549-A Developing method of image-formation device, and developing mechanism using said method RICOH KK (JP) 2003-08-27 CN disclosed
CN-1405640-A Electronic photographic photo-receptor, image-forming method and instrument, and film cartridge for treatment RICOH KK (JP) 2003-03-26 CN disclosed
US-6472114-B2 ELECTRIC CHARGE GENERATING MATERIAL, A BINDING RESIN, A SILICON OIL HAVING A SPECIFIED SURFACE TENSION, AND AN ORGANIC SOLVENT; FOR USE WITH COPIERS, A PRINTER OR A FACSIMILE SHARP KABUSHIKI KAISHA (JP) 2002-10-29 US disclosed
US-20020051921-A1 Coating fluid for electric charge generating layer, organic electrophotographic receptor, and method fo manufacturing the same SHARP KABUSHIKI KAISHA (JP) 2002-05-02 US disclosed
EP-0767411-A1 Electrophotographic photoconductor for use with liquid toners LEXMARK INTERNATIONAL, INC. (US) 1997-04-09 EP disclosed
US-4702979-A ELECTROCONDUCTIVE CATHODE LAYER, PHOTOCONDUCTIVE LAYER OF CHARGE-GENERATING ORGANIC PIGMENT, ANODIC ION REACTION AT INTERFACE WHEN IRRADIATED RICOH CO., LTD. (JP) 1987-10-27 US disclosed
JP-S56150749-A ELECTROPHOTOGRAPHIC RECEPTOR RICOH CO LTD 1981-11-21 JP disclosed