SCHEMBL4407604

SCHEMBL4407604

c1ccc(CN(Cc2ccccc2)c2ccc(CCc3ccc(CCc4ccc(N(Cc5ccccc5)Cc5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.67
TSHR P16473 4/20 0.57
CNR2 P34972 4/20 0.57
NR1H2 P55055 3/20 0.53
NR1H3 Q13133 3/20 0.53
NR3C1 P04150 1/20 0.51
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
CYP2D6 P10635 2/20 0.47
TAAR1 Q96RJ0 2/20 0.47
LMNA P02545 2/20 0.47
CYP1A2 P05177 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
PDE6A P16499 1/20 0.47
ADRA2C P18825 1/20 0.47
MC4R P32245 1/20 0.47
ADRA1A P35348 1/20 0.47
HRH1 P35367 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379145 0.91 CYP2C19 (0.62) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL2960872 0.91 CYP2C19 (0.78) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL14283665 0.90 CYP2C19 (0.61) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL4400874 0.88 TSHR (0.78) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL135570 0.88 CYP2C19 (0.63) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL3747682 0.88 TDP1 (0.61) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL10763738 0.86 CYP2C19 (0.67) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL14283605 0.86 TSHR (0.75) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL14074811 0.86 CYP2C19 (0.56) CYP2C19TSHRCNR2NR1H2NR1H3
SCHEMBL43183 0.85 TSHR (0.74) CYP2C19TSHRCNR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 US disclosed
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 US disclosed
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-8173343-B2 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
US-7964327-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming apparatus, image forming method and process cartridge using the photoreceptor RICOH COMPANY LTD. (JP) 2011-06-21 US disclosed
US-7729634-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2010-06-01 US disclosed
US-20100015538-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS USING THE SAME, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2010-01-21 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080219694-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-09-11 US disclosed
US-7381511-B2 Photoreceptor, image forming method and image forming apparatus using the photoreceptor, process cartridge using the photoreceptor and coating liquid for the photoreceptor RICOH COMPANY, LTD. (JP) 2008-06-03 US disclosed
US-7381511-B2 Photoreceptor, image forming method and image forming apparatus using the photoreceptor, process cartridge using the photoreceptor and coating liquid for the photoreceptor RICOH COMPANY, LTD. (JP) 2008-06-03 US disclosed
US-20080113285-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-05-15 US disclosed
US-20080112742-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-05-15 US disclosed
US-20070287083-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY LTD. (JP) 2007-12-13 US disclosed
US-20070287083-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY LTD. (JP) 2007-12-13 US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212626-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed