Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | PNP | P00491 | 3/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.46 |
| ▸ | TK1 | P04183 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21000304 | 1.00 | ADORA3 (0.53) | ADORA3PNPHPRT1POLBSTING1 | |
| SCHEMBL13794857 | 0.81 | PNP (0.52) | ADORA3PNPHPRT1POLBSTING1 | |
| SCHEMBL880201 | 0.81 | PNP (0.48) | ADORA3PNPHPRT1STING1TK1 | |
| SCHEMBL22278899 | 0.81 | ADORA3 (0.52) | ADORA3PNPHPRT1POLBSTING1 | |
| SCHEMBL22110944 | 0.81 | ADORA3 (0.52) | ADORA3PNPHPRT1POLBSTING1 | |
| SCHEMBL24257989 | 0.81 | ADORA3 (0.52) | ADORA3PNPHPRT1POLBSTING1 | |
| SCHEMBL9471250 | 0.80 | PNP (0.57) | ADORA3PNPHPRT1POLBSTING1 | |
| Entecavir Anhydrous SCHEMBL21510623 | 0.80 | ADORA3 (0.52) | ADORA3PNPHPRT1POLBSTING1 | |
| Entecavir Anhydrous SCHEMBL19644968 | 0.80 | ADORA3 (0.52) | ADORA3PNPHPRT1POLBSTING1 | |
| Entecavir Anhydrous SCHEMBL24726395 | 0.80 | ADORA3 (0.52) | ADORA3PNPHPRT1POLBSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594569-A1 | ENTECAVIR SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2013-05-22 | — | — | EP | disclosed |
| EP-1644384-B1 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF ENTECAVIR | BRISTOL MYERS SQUIBB CO (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2007030657-A1 | CRYSTALLINE FORMS OF [1S-(1α, 3α, 4β)]-2- AMINO-1,9-DIHYDRO-9-[4-HYDROXY-3-(HYDROXYMETHYL)-2- METHYLENECYCLOPENTYL]-6H-PURIN-6-ONE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-15 | — | — | WO | disclosed |