Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893613 | 0.84 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL20764223 | 0.81 | ALDH1A1 (0.60) | ALDH1A1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL4897438 | 0.79 | ALDH1A1 (0.64) | ALDH1A1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL23091255 | 0.77 | CYP1A2 (0.69) | ALDH1A1MAPTSMN1; SMN2NPC1HSD17B1 | |
| SCHEMBL31337212 | 0.77 | PTPN1 (0.64) | ALDH1A1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL1313933 | 0.76 | NR4A1 (0.69) | ALDH1A1MAPTHSD17B1HSD17B2KDM4E | |
| SCHEMBL4896955 | 0.76 | ALDH1A1 (0.67) | ALDH1A1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL1317340 | 0.76 | HSD17B1 (0.55) | ALDH1A1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL4893495 | 0.75 | ALDH1A1 (0.61) | ALDH1A1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL20764349 | 0.73 | MAPT (0.62) | ALDH1A1RAB9AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277444-A1 | SYNTHESIS OF HYDROXYALKYL AMIDES FROM ESTERS | JOHNSON & JOHNSON VISION CARE, INC. | 2012-11-01 | — | — | US | disclosed |
| US-20120277444-A1 | SYNTHESIS OF HYDROXYALKYL AMIDES FROM ESTERS | JOHNSON & JOHNSON VISION CARE, INC. | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277444-A1 | SYNTHESIS OF HYDROXYALKYL AMIDES FROM ESTERS | HDHD5, HACL2, HRH3 | ALDH1A1 348/4885RAB9A 3840/4885MAPT 4235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.