SCHEMBL1355967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12137363	0.78	MAPT (0.60)	NR1H2LMNATSHRMAPTNR1H3
	SCHEMBL1779589	0.76	CA9 (0.59)	CA9NR1H2TSHRMAPTALDH1A1
	SCHEMBL9941326	0.76	CA9 (0.82)	CA9CHRNA7NR1H2
	SCHEMBL1156322	0.76	NOD2 (0.50)	CA9NOD2NOD1CHRNA7LMNA
	SCHEMBL9941851	0.76	CA9 (1.00)	CA9CHRNA7SMN1; SMN2
	SCHEMBL14288144	0.75	FAAH (0.58)	CA9NR1H2TSHRMAPTALDH1A1
	SCHEMBL4016328	0.74	CA9 (0.57)	CA9NR1H2TSHRMAPTALDH1A1
	SCHEMBL28804760	0.74	CA9 (0.57)	CA9NR1H2TSHRL3MBTL1MAPT
	SCHEMBL9630738	0.74	CA9 (0.77)	CA9CHRNA7MAPTKMT2AGAA
	SCHEMBL9210036	0.74	CA9 (0.75)	CA9CHRNA7NR1H2KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.