Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PLEC | Q15149 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27686457 | 0.98 | ALDH1A1 (0.47) | ALDH1A1MAPTTHRBKDM4EGAA | |
| SCHEMBL8898753 | 0.81 | CYP3A4 (0.52) | ALDH1A1MAPTTHRBKDM4EGAA | |
| SCHEMBL28621184 | 0.79 | HCAR3 (0.40) | HCAR3HDAC6 | |
| SCHEMBL28636219 | 0.77 | PRSS1 (0.41) | HCAR3HDAC6 | |
| SCHEMBL28615286 | 0.77 | PRSS1 (0.41) | HCAR3HDAC6 | |
| SCHEMBL16867408 | 0.77 | CYP3A4 (0.50) | ALDH1A1MAPTTHRBKDM4EGAA | |
| SCHEMBL8036530 | 0.76 | KDM4E (0.41) | ALDH1A1MAPTTHRBKDM4EGAA | |
| SCHEMBL10433150 | 0.76 | KDM4E (0.41) | ALDH1A1MAPTTHRBKDM4EGAA | |
| SCHEMBL6270848 | 0.76 | CYP3A4 (0.39) | ALDH1A1MAPTTHRBKDM4EGAA | |
| SCHEMBL2273254 | 0.74 | CYP3A4 (0.38) | ALDH1A1MAPTTHRBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103641794-B | Sulfonium compound and application thereof | 维斯塔实验室有限公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-101460157-B | protein aggregation inhibitors | WISTA LABORATORIES LTD. (SG) | 2015-09-02 | — | — | CN | disclosed |
| CN-103735554-A | Inhibitors of protein aggregation | WISTA LAB LTD | 2014-04-23 | — | — | CN | disclosed |
| CN-103641794-A | Sulfonium compounds and their use | WISTA LAB LTD | 2014-03-19 | — | — | CN | disclosed |
| CN-101460222-B | Sulfonium compounds and their use | WISTA LAB LTD | 2013-12-04 | — | — | CN | disclosed |
| US-8507546-B2 | Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2013-08-13 | — | — | US | disclosed |
| US-8507546-B2 | Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2013-08-13 | — | — | US | disclosed |
| US-20120276121-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2012-11-01 | — | — | US | disclosed |
| US-20120276121-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2012-11-01 | — | — | US | disclosed |
| US-20090324580-A1 | Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases | CENIX BIOSCIENCE GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| US-20090324580-A1 | Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases | CENIX BIOSCIENCE GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| CN-101460222-A | Sulfonium compounds and their use | WISTA LAB LTD (SG) | 2009-06-17 | — | — | CN | disclosed |
| CN-101460157-A | Protein aggregation inhibitors | WISTA LAB LTD (SG) | 2009-06-17 | — | — | CN | disclosed |
| CN-1010347-B | Method for improving ammonia development rate of diazo blueprint paper | STATE CHANGSH CHEMICAL PHOTOGR (CN) | 1990-11-07 | — | — | CN | disclosed |
| CN-1030828-A | Improve the method for ammonia developing rate of heavy-nitrogen printing paper | STATE OWNED CHANGSHA CHEMICAL (CN) | 1989-02-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324580-A1 | Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases | SCARB1, MSR1, HAVCR2 | ALDH1A1 511/4885MAPT 4202/4885THRB 901/4885 |
| US-20120276121-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | SCARB1, MSR1, HAVCR2 | ALDH1A1 511/4885MAPT 4202/4885THRB 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.