SCHEMBL28615286

SCHEMBL28615286

CCCCCCNc1ccc(N)c(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 6/20 0.41
HCAR3 P49019 1/20 0.40
TLR8 Q9NR97 1/20 0.39
HDAC6 Q9UBN7 1/20 0.38
PLK1 P53350 2/20 0.38
CISD1 Q9NZ45 5/20 0.37
NQO2 P16083 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28636219 1.00 PRSS1 (0.41) PRSS1HCAR3TLR8HDAC6PLK1
SCHEMBL28621184 0.98 HCAR3 (0.40) PRSS1HCAR3TLR8HDAC6PLK1
SCHEMBL27542122 0.82 HCAR3 (0.41) HCAR3PLK1CISD1
SCHEMBL9690904 0.81 KDM6B (0.46) HCAR3TLR8
Iodide SCHEMBL27772285 0.81 HCAR3 (0.40) HCAR3PLK1CISD1
SCHEMBL29045180 0.79 TYR (0.47) HCAR3PLK1CISD1
SCHEMBL21016436 0.78 HDAC6 (0.61) PRSS1HDAC6PLK1
SCHEMBL13560937 0.77 ALDH1A1 (0.49) HCAR3HDAC6
SCHEMBL15928731 0.77 TLR8 (0.46) TLR8HDAC6
SCHEMBL21841848 0.76 HDAC6 (0.48) TLR8HDAC6PLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114606012-A Polymerizable liquid crystal material and polymerized liquid crystal film 默克专利股份有限公司 2022-06-10 CN disclosed
CN-113785032-A Reactive mesogen 默克专利股份有限公司 2021-12-10 CN disclosed
CN-113646411-A Polymerizable liquid crystal material and polymerized liquid crystal film 默克专利股份有限公司 2021-11-12 CN disclosed
CN-113302262-A Method for preparing liquid crystal polymer film 默克专利股份有限公司 2021-08-24 CN disclosed
CN-107690468-B Reactive mesogen 默克专利股份有限公司 2021-08-20 CN disclosed