Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 6/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565617 | 0.91 | MET (0.40) | METMEN1KMT2ANPC1RAB9A | |
| SCHEMBL17090343 | 0.91 | MET (0.40) | METMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13565511 | 0.82 | GRIA2 (0.43) | METMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10114264 | 0.82 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL13565752 | 0.77 | NPC1 (0.38) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL17090253 | 0.77 | NPC1 (0.38) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL11934838 | 0.76 | KDM4E (0.42) | METMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13438688 | 0.76 | KDM4E (0.42) | METMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11936220 | 0.76 | NR3C1 (0.42) | METMEN1KMT2ANPC1CNR2 | |
| SCHEMBL13565703 | 0.76 | NR3C1 (0.42) | METMEN1KMT2ANPC1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |