Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090343 | 1.00 | MET (0.40) | METMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13565103 | 0.91 | MET (0.39) | METMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13565511 | 0.85 | GRIA2 (0.43) | METMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11936220 | 0.84 | NR3C1 (0.42) | METMEN1KMT2ANPC1CNR2 | |
| SCHEMBL13565703 | 0.84 | NR3C1 (0.42) | METMEN1KMT2ANPC1CNR2 | |
| SCHEMBL13203762 | 0.80 | NPY5R (0.50) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL10113218 | 0.80 | NPY5R (0.50) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL13564865 | 0.79 | ALDH1A1 (0.39) | MEN1KMT2ACNR2 | |
| SCHEMBL17090359 | 0.79 | ALDH1A1 (0.39) | MEN1KMT2ACNR2 | |
| SCHEMBL13565810 | 0.79 | MEN1 (0.43) | MEN1KMT2AKDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |