Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090001 | 1.00 | LMNA (0.45) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL17090005 | 0.88 | SMN1; SMN2 (0.53) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL13565315 | 0.88 | SMN1; SMN2 (0.53) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL17089940 | 0.85 | ALDH1A1 (0.43) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL13565597 | 0.85 | ALDH1A1 (0.43) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL13439243 | 0.85 | MEN1 (0.45) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL17089992 | 0.84 | DDIT3 (0.43) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL13565738 | 0.84 | DDIT3 (0.43) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL17089942 | 0.84 | ALDH1A1 (0.41) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL13565473 | 0.84 | ALDH1A1 (0.41) | LMNAGAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |