Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935498 | 0.88 | SMN1; SMN2 (0.53) | MEN1KMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL13439232 | 0.88 | SMN1; SMN2 (0.53) | MEN1KMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL17090001 | 0.85 | LMNA (0.45) | MEN1KMT2AALDH1A1USP2TDP1 | |
| SCHEMBL13565152 | 0.85 | LMNA (0.45) | MEN1KMT2AALDH1A1USP2TDP1 | |
| SCHEMBL11935083 | 0.84 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1USP2TDP1 | |
| SCHEMBL13565866 | 0.84 | DDIT3 (0.43) | MEN1KMT2AALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL13565240 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17090423 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13565425 | 0.83 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1USP2TDP1 | |
| SCHEMBL13564972 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1USP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150507-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-9150507-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-20100063027-A1 | Amine Derivative Having NPY Y5 Receptor Antagonistic Activity | SHIONOGI & CO., LTD. (JP) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063027-A1 | Amine Derivative Having NPY Y5 Receptor Antagonistic Activity | NPY5R, NPY1R, NPY2R | MEN1 1550/4885KMT2A 2031/4885ALDH1A1 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.