Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10116638 | 0.90 | KMT2A (0.60) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13565362 | 0.89 | RAB9A (0.48) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10116668 | 0.85 | NPC1 (0.56) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13566054 | 0.85 | HPGD (0.51) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10116642 | 0.83 | KMT2A (0.50) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13565069 | 0.83 | ALDH1A1 (0.53) | NPC1RAB9AALDH1A1KMT2ANAMPT | |
| SCHEMBL11936004 | 0.80 | EPHX1 (0.60) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13565340 | 0.80 | ENPP3 (0.50) | HPGDSMN1; SMN2RAB9AALDH1A1KMT2A | |
| SCHEMBL13565840 | 0.80 | ALDH1A1 (0.58) | HPGDSMN1; SMN2ALDH1A1KMT2ANAMPT | |
| SCHEMBL13565359 | 0.79 | MAPT (0.48) | SMN1; SMN2RAB9AALDH1A1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |