Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090321 | 1.00 | CRHR1 (0.39) | CRHR1CNR2CNR1PLK1VCP | |
| SCHEMBL13565131 | 1.00 | CRHR1 (0.39) | CRHR1CNR2CNR1PLK1VCP | |
| SCHEMBL17089998 | 1.00 | CRHR1 (0.39) | CRHR1CNR2CNR1PLK1VCP | |
| SCHEMBL13438902 | 0.92 | CRHR1 (0.44) | CRHR1CNR2CNR1GBA1ALDH1A1 | |
| SCHEMBL11935223 | 0.92 | CRHR1 (0.44) | CRHR1CNR2CNR1GBA1ALDH1A1 | |
| SCHEMBL17090071 | 0.90 | CNR2 (0.46) | CRHR1CNR2CNR1GBA1ALDH1A1 | |
| SCHEMBL13564943 | 0.90 | CNR2 (0.46) | CRHR1CNR2CNR1GBA1ALDH1A1 | |
| SCHEMBL13565600 | 0.87 | ALDH1A1 (0.42) | CRHR1CNR2CNR1ALDH1A1ACHE | |
| SCHEMBL17089944 | 0.87 | ALDH1A1 (0.42) | CRHR1CNR2CNR1ALDH1A1ACHE | |
| SCHEMBL17090516 | 0.87 | CRHR1 (0.47) | CRHR1CNR2CNR1ALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |