Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564943 | 1.00 | CNR2 (0.46) | CNR2CNR1ALDH1A1ALDH3A1CRHR1 | |
| SCHEMBL13438902 | 0.95 | CRHR1 (0.44) | CNR2CNR1ALDH1A1ALDH3A1CRHR1 | |
| SCHEMBL11935223 | 0.95 | CRHR1 (0.44) | CNR2CNR1ALDH1A1ALDH3A1CRHR1 | |
| SCHEMBL13565614 | 0.90 | CRHR1 (0.39) | CNR2CNR1ALDH1A1ALDH3A1CRHR1 | |
| SCHEMBL17090321 | 0.90 | CRHR1 (0.39) | CNR2CNR1ALDH1A1ALDH3A1CRHR1 | |
| SCHEMBL17089998 | 0.90 | CRHR1 (0.39) | CNR2CNR1ALDH1A1ALDH3A1CRHR1 | |
| SCHEMBL13565131 | 0.90 | CRHR1 (0.39) | CNR2CNR1ALDH1A1ALDH3A1CRHR1 | |
| SCHEMBL13565600 | 0.87 | ALDH1A1 (0.42) | CNR2CNR1ALDH1A1CRHR1NPY5R | |
| SCHEMBL17089944 | 0.87 | ALDH1A1 (0.42) | CNR2CNR1ALDH1A1CRHR1NPY5R | |
| SCHEMBL17090516 | 0.87 | CRHR1 (0.47) | CNR2CNR1ALDH1A1CRHR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |