Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 11/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090394 | 1.00 | GHSR (0.39) | GHSRNPY5RHTR1AKCNH2BRD4 | |
| SCHEMBL17090267 | 0.87 | MAPT (0.44) | NPY5RBRD4 | |
| SCHEMBL11940986 | 0.87 | MAPT (0.44) | NPY5RBRD4 | |
| SCHEMBL11934925 | 0.87 | MAPT (0.44) | NPY5RBRD4 | |
| SCHEMBL11935720 | 0.85 | HTR1A (0.51) | GHSRNPY5RHTR1AKCNH2BRD4 | |
| SCHEMBL11940090 | 0.85 | HTR1A (0.51) | GHSRNPY5RHTR1AKCNH2BRD4 | |
| SCHEMBL10134444 | 0.85 | GAA (0.48) | HTR1AKCNH2HTR7SIGMAR1USP2 | |
| SCHEMBL10114977 | 0.85 | GAA (0.48) | HTR1AKCNH2HTR7SIGMAR1USP2 | |
| SCHEMBL13565248 | 0.84 | SMN1; SMN2 (0.44) | NPY5RUSP2GAA | |
| SCHEMBL17090270 | 0.84 | SMN1; SMN2 (0.44) | NPY5RUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |