SCHEMBL1356618

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1355924	0.90	CCND3 (0.55)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL1354649	0.89	CCND3 (0.54)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL1355793	0.87	CDK4 (0.53)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL1353806	0.83	CDK4 (0.55)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL12801997	0.80	JAK3 (0.49)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL23441285	0.79	CCND3 (0.53)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL30388179	0.79	CCND3 (0.53)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL12802026	0.77	CCND3 (0.44)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL12639344	0.76	CDK4 (0.69)	CDK4CCND1CCND3CCND2CDK2
	SCHEMBL1355734	0.76	CDK4 (0.69)	CDK4CCND1CCND3CCND2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.