Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.57 |
| ▸ | CES1 | P23141 | 4/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614403 | 1.00 | CES2 (0.57) | CES2CES1PARP10MCL1BCL2L1 | |
| SCHEMBL13569209 | 1.00 | CES2 (0.57) | CES2CES1PARP10MCL1BCL2L1 | |
| SCHEMBL4189871 | 0.89 | PARP10 (0.69) | CES2CES1PARP10SRD5A2SMN1; SMN2 | |
| SCHEMBL9250736 | 0.89 | CES2 (0.71) | CES2CES1PARP10SRD5A2MAPT | |
| SCHEMBL13567254 | 0.89 | CES2 (0.71) | CES2CES1PARP10SRD5A2MAPT | |
| SCHEMBL2134251 | 0.89 | CES2 (0.71) | CES2CES1PARP10SRD5A2MAPT | |
| SCHEMBL12757139 | 0.88 | SRD5A2 (0.71) | PARP10MCL1BCL2L1SRD5A2MAPT | |
| SCHEMBL9452100 | 0.88 | SRD5A2 (0.71) | PARP10MCL1BCL2L1SRD5A2MAPT | |
| SCHEMBL11419154 | 0.88 | SRD5A2 (0.71) | PARP10MCL1BCL2L1SRD5A2PARP15 | |
| SCHEMBL9242631 | 0.87 | CES2 (0.68) | CES2CES1PARP10SRD5A2ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |