Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.69 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.67 |
| ▸ | CES2 | O00748 | 4/20 | 0.64 |
| ▸ | CES1 | P23141 | 4/20 | 0.64 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.58 |
| ▸ | FEN1 | P39748 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | BAX | Q07812 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.54 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.54 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242631 | 0.98 | CES2 (0.68) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL13567254 | 0.95 | CES2 (0.71) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL2134251 | 0.95 | CES2 (0.71) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL9250736 | 0.95 | CES2 (0.71) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL9807208 | 0.91 | PARP10 (0.64) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL4166171 | 0.91 | PARP10 (0.64) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL11034320 | 0.90 | AKR1C3 (0.61) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL13569201 | 0.89 | CES2 (0.57) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL14614403 | 0.89 | CES2 (0.57) | PARP10SRD5A2CES2CES1ERCC5 | |
| SCHEMBL13569209 | 0.89 | CES2 (0.57) | PARP10SRD5A2CES2CES1ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476416-B1 | MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-12-30 | — | — | EP | disclosed |
| EP-1476416-B1 | MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-12-30 | — | — | EP | disclosed |
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |
| US-7585928-B2 | monomers of acetylenic homo- or copolymers; cured polymers has low dielectric constant as insulating layers in microelectronic devices | DOW GLOBAL TECHNOLOGIES (US) | 2009-09-08 | — | — | US | disclosed |
| US-7585928-B2 | monomers of acetylenic homo- or copolymers; cured polymers has low dielectric constant as insulating layers in microelectronic devices | DOW GLOBAL TECHNOLOGIES (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2007-02-01 | — | — | US | disclosed |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2007-02-01 | — | — | US | disclosed |
| US-6979737-B1 | Quinoxaline-containing AB2 monomer for hyperbranched aromatic poly(ether-ketones) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2005-12-27 | — | — | US | disclosed |
| EP-0401296-B1 | RIGID-ROD POLYMERS | MAXDEM INC (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5659005-A | Rigid-rod polymers | MAXDEM INCORPORATED (US) | 1997-08-19 | — | — | US | disclosed |
| US-5565543-A | Rigid-rod polymers | MAXDEM INCORPORATED (US) | 1996-10-15 | — | — | US | disclosed |
| US-5227457-A | Rigid-rod polymers | MAXDEM INCORPORATED (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0489085-A4 | RIGID-ROD POLYMERS | MAXDEM INC (US) | 1992-08-05 | — | — | EP | disclosed |
| EP-0489085-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1992-06-10 | — | — | EP | disclosed |
| EP-0401296-A4 | RIGID-ROD POLYMERS | MAXDEM INC (US) | 1992-03-18 | — | — | EP | disclosed |
| WO-1991002764-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1991-03-07 | — | — | WO | disclosed |
| EP-0401296-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1990-12-12 | — | — | EP | disclosed |
| WO-1989007617-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1989-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | LRBA, CD74, BMP2 | PARP10 330/4885SRD5A2 1699/4885CES2 1665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.