Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.71 |
| ▸ | CES1 | P23141 | 7/20 | 0.71 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.54 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.54 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567254 | 1.00 | CES2 (0.71) | CES2CES1PARP10SRD5A2AKR1C3 | |
| SCHEMBL9250736 | 1.00 | CES2 (0.71) | CES2CES1PARP10SRD5A2AKR1C3 | |
| SCHEMBL9242631 | 0.98 | CES2 (0.68) | CES2CES1PARP10SRD5A2AKR1C3 | |
| SCHEMBL4189871 | 0.95 | PARP10 (0.69) | CES2CES1PARP10SRD5A2AKR1C3 | |
| SCHEMBL11126420 | 0.90 | CES2 (0.61) | CES2CES1PARP10SRD5A2PGR | |
| SCHEMBL11034320 | 0.90 | AKR1C3 (0.61) | CES2CES1PARP10SRD5A2AKR1C3 | |
| SCHEMBL13569209 | 0.89 | CES2 (0.57) | CES2CES1PARP10SRD5A2ALDH1A1 | |
| SCHEMBL13569201 | 0.89 | CES2 (0.57) | CES2CES1PARP10SRD5A2ALDH1A1 | |
| SCHEMBL14614403 | 0.89 | CES2 (0.57) | CES2CES1PARP10SRD5A2ALDH1A1 | |
| SCHEMBL9250355 | 0.87 | CES2 (0.60) | CES2CES1PARP10SRD5A2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5207577-A | Dental adhesive | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | claimed |
| EP-0110465-B1 | BIPHENYLENE END-CAPPED QUINOXALINE POLYMERS AND THEIR USE AS INSULATING COATINGS FOR SEMICONDUCTOR DEVICES | International Business Machines Corporation (US) | 1993-01-20 | — | — | EP | claimed |
| EP-0110465-A2 | Biphenylene end-capped quinoxaline polymers and their use as insulating coatings for semiconductor devices | International Business Machines Corporation (US) | 1984-06-13 | — | — | EP | claimed |
| US-10894848-B2 | Polyarylene resins | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2021-01-19 | — | — | US | disclosed |
| EP-3336126-A1 | POLYARYLENE RESINS | Rohm and Haas Electronic Materials LLC (US) | 2018-06-20 | — | — | EP | disclosed |
| US-20180162968-A1 | POLYARYLENE RESINS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2018-06-14 | — | — | US | disclosed |
| EP-1476416-B1 | MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-12-30 | — | — | EP | disclosed |
| US-20150191607-A1 | Anti-fouling Paints and Coatings | REACTIVE SURFACES, LTD (US) | 2015-07-09 | — | — | US | disclosed |
| US-20140196631-A1 | VISUAL ASSAYS FOR COATINGS INCORPORATING BIOACTIVE ENZYMES FOR CATALYTIC FUNCTIONS | REACTIVE SURFACE, LTD. (US) | 2014-07-17 | — | — | US | disclosed |
| EP-2039683-B1 | Vasculostatic agents and methods of use thereof | TARGEGEN INC (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20120097194-A1 | Polymeric Coatings Incorporating Bioactive Enzymes for Catalytic Function | REACTIVE SURFACES, LTD. (US) | 2012-04-26 | — | — | US | disclosed |
| US-4304898-A | HEAT RESIST METAL WIRE COATINGS | INSTITUT FRANCAIS DU PETROLE (FR) | 1981-12-08 | — | — | US | disclosed |
| US-4159251-A | Ultrafiltration membranes based on heteroaromatic polymers | PHARMACO, INC. (US) | 1979-06-26 | — | — | US | disclosed |
| US-4147868-A | AEROSPACE POLYMERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1979-04-03 | — | — | US | disclosed |
| US-4098825-A | ACETYLENE-SUBSTITUTED AROMATIC BENZILS AND ACETYLENE-TERMINATED QUINOXALINE COMPOSITIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1978-07-04 | — | — | US | disclosed |
| US-4086232-A | PLASTICIZERS FOR THERMOPLASTIC RESINS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1978-04-25 | — | — | US | disclosed |
| US-4084970-A | Organic volume phase holographic recording media using sucrose benzoate | RCA CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4076634-A | Composition for antifriction material | KORSHAK VASILY VLADIMIROVICH | 1978-02-28 | — | — | US | disclosed |
| US-4022746-A | CONDENSATION, AROMATIC DIGLYOXYL OR DIBENZIL, ORTHO-DIAMINE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1977-05-10 | — | — | US | disclosed |
| US-3944614-A | 2,2'-Bis(phenylethynyl-5,5'-diaminobenzidine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894848-B2 | Polyarylene resins | PIN1, HSD17B12, PCBP1 | CES2 299/4885CES1 748/4885PARP10 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.