Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569407 | 0.96 | TSHR (0.36) | TSHRCYP2C9MCHR1POLBTDP1 | |
| SCHEMBL13569398 | 0.92 | THRB (0.37) | ARPOLBTDP1APEX1HTT | |
| SCHEMBL13569404 | 0.92 | AR (0.34) | TSHRARPOLBTDP1KMT2A | |
| SCHEMBL13569417 | 0.92 | MAPT (0.37) | ARPOLBTDP1APEX1HTT | |
| SCHEMBL13569405 | 0.91 | MAPT (0.37) | ARPOLBTDP1APEX1HTT | |
| SCHEMBL13569411 | 0.89 | CHKA (0.34) | ARPOLBTDP1APEX1HTT | |
| SCHEMBL13569432 | 0.89 | AR (0.38) | ARMMP1MMP2 | |
| SCHEMBL13569414 | 0.89 | THRB (0.37) | ARPOLBTDP1APEX1HTT | |
| SCHEMBL13569397 | 0.89 | AR (0.32) | ARPOLBTDP1APEX1HTT | |
| SCHEMBL13569406 | 0.89 | MAPT (0.35) | CYP2C9ARPOLBTDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629094-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2009-12-08 | — | — | US | disclosed |