Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397188 | 0.80 | CTSC (0.49) | NPC1RAB9AGAATSHR | |
| SCHEMBL13570736 | 0.80 | CCNA2 (0.50) | GAACCNA2CDK2CCNA1 | |
| SCHEMBL22557469 | 0.80 | CES2 (0.50) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL22557224 | 0.80 | CES2 (0.50) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL22557226 | 0.80 | CES2 (0.50) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7511740 | 0.79 | GPR6 (0.46) | GPR6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5213635 | 0.76 | KDM4E (0.53) | RAB9AALDH1A1 | |
| SCHEMBL7422574 | 0.76 | PDE4D (0.58) | — | |
| SCHEMBL7517030 | 0.76 | CDC25B (0.46) | RAB9A | |
| SCHEMBL11121066 | 0.76 | KDM4E (0.47) | RAB9AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519506-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-11-07 | — | — | EP | claimed |