Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | HTR7 | P34969 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874840 | 1.00 | DPP4 (0.49) | DPP4HTR1AHTR7PARP1VNN1 | |
| SCHEMBL30874873 | 0.84 | VNN1 (0.43) | DPP4HTR1AHTR7VNN1ACE | |
| SCHEMBL30341550 | 0.84 | DPP4 (0.46) | DPP4HTR1AHTR7VNN1ACE | |
| SCHEMBL30874909 | 0.82 | VNN1 (0.47) | DPP4HTR1AHTR7VNN1 | |
| SCHEMBL10578521 | 0.81 | SMN1; SMN2 (0.48) | DPP4PARP1HSD11B1NPC1HRH3 | |
| SCHEMBL6443274 | 0.80 | CASP3 (0.48) | DPP4HSD11B1NPC1POLBHRH3 | |
| SCHEMBL474918 | 0.80 | DPP4 (0.57) | DPP4HTR1AHTR7NPC1POLB | |
| SCHEMBL2177077 | 0.80 | DPP4 (0.57) | DPP4HTR1AHTR7NPC1POLB | |
| SCHEMBL845195 | 0.78 | HCRTR1 (0.46) | HSD11B1 | |
| SCHEMBL4927632 | 0.77 | L3MBTL1 (0.53) | VNN1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519506-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-11-07 | — | — | EP | claimed |