SCHEMBL1357280

SCHEMBL1357280

C=CC(=O)OCCC1(c2ccccc2)CCO1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
GAA P10253 1/20 0.40
TSHR P16473 7/20 0.39
ALDH1A1 P00352 5/20 0.37
TP53 P04637 2/20 0.37
HIF1A Q16665 2/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
ICMT O60725 3/20 0.36
CYP2C19 P33261 2/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 3/20 0.35
TET3 O43151 1/20 0.35
FBXL19 Q6PCT2 1/20 0.35
CXXC5 Q7LFL8 1/20 0.35
TET1 Q8NFU7 1/20 0.35
KDM2B Q8NHM5 1/20 0.35
CXXC4 Q9H2H0 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
OPRM1 P35372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1357941 0.86 THRB (0.43) THRBGAATSHRALDH1A1CYP3A4
SCHEMBL243069 0.84 GAA (0.41) GAATSHRALDH1A1ICMTCYP2C19
SCHEMBL245947 0.81 GAA (0.43) THRBGAATSHRALDH1A1ICMT
SCHEMBL1357657 0.77 THRB (0.49) THRBGAATSHRALDH1A1TP53
SCHEMBL17839038 0.72 TSHR (0.44) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL27706841 0.72 TSHR (0.44) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL11763694 0.71 TSHR (0.46) THRBGAATSHRALDH1A1CYP3A4
SCHEMBL245007 0.70 GAA (0.40) GAATSHRALDH1A1ICMTCYP2C19
SCHEMBL1356956 0.70 TSHR (0.46) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL28909719 0.69 POLB (0.41) THRBGAATSHRALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115437214-A Chemically amplified positive photosensitive resin composition, protective film, and element having protective film 奇美实业股份有限公司 2022-12-06 CN disclosed
US-20110281040-A1 LIQUID CRYSTAL DISPLAY ELEMENT, POSITIVE TYPE RADIATION SENSITIVE COMPOSITION, INTERLAYER INSULATING FILM FOR LIQUID CRYSTAL DISPLAY ELEMENT, AND FORMATION METHOD THEREOF JSR CORPORATION (JP) 2011-11-17 US disclosed