Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357135 | 0.87 | THRB (0.45) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL1357847 | 0.80 | GAA (0.40) | THRBTSHRALDH1A1CYP3A4GAA | |
| SCHEMBL1357280 | 0.77 | THRB (0.48) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL28226362 | 0.71 | THRB (0.44) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL2132862 | 0.71 | TSHR (0.46) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL1357941 | 0.70 | THRB (0.43) | THRBTSHRALDH1A1CYP3A4GAA | |
| SCHEMBL5031526 | 0.70 | MAOA (0.41) | — | |
| SCHEMBL3380377 | 0.70 | ACSS2 (0.43) | TSHRCYP2D6HTTSMN1; SMN2 | |
| SCHEMBL25249338 | 0.70 | KEAP1 (0.38) | TSHRALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL28357984 | 0.69 | THRB (0.43) | THRBALDH1A1GAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281040-A1 | LIQUID CRYSTAL DISPLAY ELEMENT, POSITIVE TYPE RADIATION SENSITIVE COMPOSITION, INTERLAYER INSULATING FILM FOR LIQUID CRYSTAL DISPLAY ELEMENT, AND FORMATION METHOD THEREOF | JSR CORPORATION (JP) | 2011-11-17 | — | — | US | disclosed |