Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613738 | 0.86 | TTBK1 (0.39) | TTBK1P2RX3P2RX2PIK3CARPS6KA5 | |
| SCHEMBL12743214 | 0.80 | TTBK1 (0.37) | TTBK1P2RX3P2RX2PIK3CAFFAR4 | |
| SCHEMBL1613405 | 0.76 | MAP3K14 (0.44) | TTBK1 | |
| SCHEMBL13575032 | 0.75 | JAK2 (0.34) | TTBK1P2RX3P2RX2DHFRHTT | |
| SCHEMBL13575034 | 0.75 | ALDH1A1 (0.33) | P2RX3P2RX2 | |
| SCHEMBL21282714 | 0.68 | RPS6KA5 (0.60) | RPS6KA5ROCK1HTTFFAR4 | |
| SCHEMBL16610267 | 0.67 | CDC7 (0.41) | TTBK1RPS6KA5ROCK1 | |
| SCHEMBL20357857 | 0.65 | TTBK1 (0.51) | TTBK1P2RX3P2RX2ROCK1DHFR | |
| SCHEMBL1612241 | 0.64 | CDC7 (0.63) | TTBK1ROCK1 | |
| SCHEMBL1613330 | 0.62 | ERN1 (0.36) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158011-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2009-12-30 | — | — | WO | disclosed |