Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.72 |
| ▸ | CCR2 | P41597 | 2/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225551 | 0.83 | ROCK2 (1.00) | ROCK2CCR2ROCK1 | |
| SCHEMBL2801924 | 0.83 | ROCK2 (1.00) | ROCK2CCR2ROCK1 | |
| SCHEMBL225552 | 0.83 | ROCK2 (1.00) | ROCK2CCR2ROCK1 | |
| SCHEMBL13106900 | 0.80 | ROCK2 (0.55) | ROCK2CCR2ROCK1 | |
| SCHEMBL3858258 | 0.76 | ROCK2 (0.51) | ROCK2CCR2ROCK1 | |
| SCHEMBL459599 | 0.75 | ROCK2 (0.83) | ROCK2CCR2ROCK1 | |
| SCHEMBL5412948 | 0.75 | ROCK2 (0.62) | ROCK2CCR2ROCK1 | |
| SCHEMBL660018 | 0.75 | ROCK2 (1.00) | ROCK2CCR2ROCK1 | |
| SCHEMBL459600 | 0.75 | ROCK2 (0.83) | ROCK2CCR2ROCK1 | |
| Hydrochloric Acid SCHEMBL5413188 | 0.74 | ROCK2 (0.61) | ROCK2CCR2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158587-A1 | METHOD FOR TREATING PULMONARY DISEASES USING RHO KINASE INHIBITOR COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |