Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.72 |
| ▸ | NPC1 | O15118 | 12/20 | 0.72 |
| ▸ | MAPT | P10636 | 10/20 | 0.72 |
| ▸ | GAA | P10253 | 8/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | CASP3 | P42574 | 2/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.72 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522459 | 0.86 | RAB9A (0.76) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL7522456 | 0.86 | RAB9A (0.76) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL4180837 | 0.84 | RAB9A (1.00) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL4180835 | 0.84 | RAB9A (1.00) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL29033673 | 0.84 | RAB9A (1.00) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL28724436 | 0.83 | RAB9A (0.71) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL28724437 | 0.83 | RAB9A (0.71) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL7853695 | 0.80 | RAB9A (0.71) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL7853699 | 0.80 | RAB9A (0.71) | RAB9ANPC1MAPTGAAMAPK1 | |
| SCHEMBL16339677 | 0.77 | CYP1A2 (0.50) | RAB9ANPC1MAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280803-A1 | RADIOIODINATION METHOD | GE HEALTHCARE UK LIMITED (GB) | 2011-11-17 | — | — | US | disclosed |
| US-20110280803-A1 | RADIOIODINATION METHOD | GE HEALTHCARE UK LIMITED (GB) | 2011-11-17 | — | — | US | disclosed |
| EP-2382185-A1 | RADIOIODINATION METHOD | GE Healthcare Limited (GB) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010086398-A1 | RADIOIODINATION METHOD | GE HEALTHCARE LIMITED (GB) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010086398-A1 | RADIOIODINATION METHOD | GE HEALTHCARE LIMITED (GB) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280803-A1 | RADIOIODINATION METHOD | TPO, SSTR5, DAO | RAB9A 1195/4885NPC1 2636/4885MAPT 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.