Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830786 | 0.74 | NPC1 (0.41) | L3MBTL1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29038863 | 0.69 | CYP2C9 (0.38) | L3MBTL1AKT1HPGDALDH1A1MEN1 | |
| SCHEMBL29038865 | 0.69 | CYP2C9 (0.38) | L3MBTL1AKT1HPGDALDH1A1MEN1 | |
| SCHEMBL15689125 | 0.68 | KMT2A (0.44) | L3MBTL1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL4185156 | 0.68 | MEN1 (0.47) | L3MBTL1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL25170278 | 0.68 | CYP1A2 (0.53) | L3MBTL1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL25170277 | 0.68 | CYP1A2 (0.53) | L3MBTL1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL15689127 | 0.68 | KMT2A (0.44) | L3MBTL1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL2626716 | 0.67 | SRR (0.62) | — | |
| SCHEMBL1486321 | 0.67 | SRR (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152474-A2 | PROCESS FOR THE PREPARATION OF (3S)-3-AMINO-N-CYCLOPROPYL-2-HYDROXYALKANAMIDE DERIVATIVES | VIROBAY, INC. (US) | 2009-12-17 | — | — | WO | disclosed |