SCHEMBL1357948

SCHEMBL1357948

CCOS(=O)(=O)N(CC)CC

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 1/20 0.43
HTT P42858 4/20 0.39
LMNA P02545 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 3/20 0.33
TSHR P16473 3/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL19971603 0.97 CA1 (0.42) CA1CA2HTTLMNASMN1; SMN2
SCHEMBL11143490 0.75 LMNA (0.34) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL11108737 0.74
SCHEMBL27100041 0.74 SMN1; SMN2 (0.35) CA1CA2HTTLMNASMN1; SMN2
SCHEMBL22883321 0.74 KDM4E (0.36) CA1CA2HTTALDH1A1TSHR
SCHEMBL21462096 0.74 CA1 (0.54) CA1CA2LMNANPC1RAB9A
SCHEMBL21423123 0.72 LMNA (0.34) CA1HTTLMNASMN1; SMN2NPC1
SCHEMBL22883621 0.72
SCHEMBL11872162 0.72
SCHEMBL7212342 0.72 CA1 (0.43) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116651502-A Sulfonated polysulfone-based ionic liquid catalytic material and preparation method thereof 北京理工大学 2023-08-29 CN claimed
US-4266048-A Synthesis of analogs of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1981-05-05 US claimed
US-4169011-A PHOSPHORYLATION OF ADENOSINE, SULFONATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1979-09-25 US claimed
CN-116651502-A Sulfonated polysulfone-based ionic liquid catalytic material and preparation method thereof 北京理工大学 2023-08-29 CN disclosed
CN-116651502-A Sulfonated polysulfone-based ionic liquid catalytic material and preparation method thereof 北京理工大学 2023-08-29 CN disclosed
US-20110288230-A1 METHOD FOR PREPARING POLYHYDROXY-URETHANES RHODIA OPERATIONS (FR) 2011-11-24 US disclosed
US-8017719-B2 Method for preparing polyhydroxy-urethanes RHODIA OPERATIONS (FR) 2011-09-13 US disclosed
US-20090312502-A1 Method for preparing polyhydroxy-urethanes RHODIA OPERATIONS (FR) 2009-12-17 US disclosed
US-6605730-B2 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula NIHON BAYER AGROCHEM K.K. (JP) 2003-08-12 US disclosed
US-20030028034-A1 Nematicidal pyrazoles WADA KATSUAKI (JP) 2003-02-06 US disclosed
US-6440691-B1 AIDS VIRICIDES LARGE SCALE BIOLOGY CORPORATION 2002-08-27 US disclosed
US-RE32261-E Process for producing thermosetting finishing powders MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1986-10-07 US disclosed
US-4387221-A Alkyl- and alkenyl-sulfosuccinate starchhalf-esters, a method for the preparation thereof NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1983-06-07 US disclosed
US-4266048-A Synthesis of analogs of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1981-05-05 US disclosed
US-4266048-A Synthesis of analogs of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1981-05-05 US disclosed
US-4242505-A S-Adenosyl-L-methionine compositions and production thereof YAMASA SHOYU KABUSHIKI KAISHA (JP) 1980-12-30 US disclosed
US-4169011-A PHOSPHORYLATION OF ADENOSINE, SULFONATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1979-09-25 US disclosed
US-4169011-A PHOSPHORYLATION OF ADENOSINE, SULFONATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1979-09-25 US disclosed
US-4042645-A ACRYLIC ESTER COPOLYMERS MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1977-08-16 US disclosed
US-3954898-A Powder coating of epoxy resin, acrylic copolymer and tertiary amine MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288230-A1 METHOD FOR PREPARING POLYHYDROXY-URETHANES UROD, HPD, ALKBH3 CA1 18/4885CA2 89/4885HTT 781/4885
US-20030028034-A1 Nematicidal pyrazoles CBR3, CBR1, CCR4 CA1 1995/4885CA2 322/4885HTT 3125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.