Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL19971603

CCOS(=O)(=O)N(CC)CC.N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.42
CA2 P00918 1/20 0.42
HTT P42858 4/20 0.38
LMNA P02545 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ALDH1A1 P00352 3/20 0.32
TSHR P16473 3/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1357948 0.97 CA1 (0.43) CA1CA2HTTLMNASMN1; SMN2
SCHEMBL11143490 0.73 LMNA (0.34) HTTLMNASMN1; SMN2NPC1RAB9A
SCHEMBL11108737 0.72
SCHEMBL27100041 0.72 SMN1; SMN2 (0.35) CA1CA2HTTLMNASMN1; SMN2
SCHEMBL22883321 0.72 KDM4E (0.36) CA1CA2HTTALDH1A1TSHR
SCHEMBL21462096 0.72 CA1 (0.54) CA1CA2LMNANPC1RAB9A
SCHEMBL21423123 0.70 LMNA (0.34) CA1HTTLMNASMN1; SMN2NPC1
SCHEMBL22883621 0.70
SCHEMBL7212342 0.70 CA1 (0.43) CA1CA2
SCHEMBL11872162 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331687-A1 Acesulfame Potassium Compositions and Processes for Producing Same CELANESE INT CORP (US) 2023-10-19 US disclosed
US-20230322698-A1 Acesulfame Potassium Compositions and Processes for Producing Same CELANESE INT CORP (US) 2023-10-12 US disclosed
US-20230322696-A1 Acesulfame Potassium Compositions and Processes for Producing Same CELANESE INT CORP (US) 2023-10-12 US disclosed
US-20230322697-A1 Acesulfame Potassium Compositions and Processes for Producing Same CELANESE INT CORP (US) 2023-10-12 US disclosed
US-11731948-B2 Acesulfame potassium compositions and processes for producing same CELANESE INTERNATIONAL CORPORATION (US) 2023-08-22 US disclosed
US-11724994-B2 Acesulfame potassium compositions and processes for producing same CELANESE INTERNATIONAL CORPORATION (US) 2023-08-15 US disclosed
US-11724993-B2 Acesulfame potassium compositions and processes for producing same CELANESE INTERNATIONAL CORPORATION (US) 2023-08-15 US disclosed
US-11718594-B2 Acesulfame potassium compositions and processes for producing same CELANESE INTERNATIONAL CORPORATION (US) 2023-08-08 US disclosed
EP-3907220-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME Celanese International Corporation (US) 2021-11-10 EP disclosed
US-20210221779-A1 Acesulfame Potassium Compositions and Processes for Producing Same CELANESE INTERNATIONAL CORPORATION 2021-07-22 US disclosed
WO-2018057389-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME CELANESE INTERNATIONAL CORPORATION (US) 2018-03-29 WO disclosed
WO-2018057386-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME CELANESE INTERNATIONAL CORPORATION (US) 2018-03-29 WO disclosed
WO-2018057388-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME CELANESE INTERNATIONAL CORPORATION (US) 2018-03-29 WO disclosed
WO-2018057387-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME CELANESE INTERNATIONAL CORPORATION (US) 2018-03-29 WO disclosed
US-20180079734-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME CELANESE INTERNATIONAL CORPORATION 2018-03-22 US disclosed
US-20180079736-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME CELANESE INTERNATIONAL CORPORATION 2018-03-22 US disclosed
US-20180079735-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME CELANESE INTERNATIONAL CORPORATION 2018-03-22 US disclosed
US-20180079733-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME CELANESE INTERNATIONAL CORPORATION 2018-03-22 US disclosed
CN-107820490-A Acesulfame potassium composition and process for producing the same 国际人造丝公司 2018-03-20 CN disclosed
CN-107820491-A Acesulfame potassium composition and process for producing the same 国际人造丝公司 2018-03-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718594-B2 Acesulfame potassium compositions and processes for producing same ACE, AGT, KCNJ1 CA1 255/4885CA2 115/4885HTT 1849/4885
US-20180079734-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME ACE, AGT, KCNJ1 CA1 255/4885CA2 115/4885HTT 1849/4885
US-11731948-B2 Acesulfame potassium compositions and processes for producing same AGT, ACE, HCN4 CA1 25/4885CA2 50/4885HTT 779/4885
US-20180079735-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME AGT, ACE, TST CA1 57/4885CA2 42/4885HTT 1866/4885
US-20230322697-A1 Acesulfame Potassium Compositions and Processes for Producing Same AGT, ACE, TST CA1 57/4885CA2 42/4885HTT 1866/4885
US-20230322696-A1 Acesulfame Potassium Compositions and Processes for Producing Same ACE, AGT, KCNJ1 CA1 255/4885CA2 115/4885HTT 1849/4885
US-20230331687-A1 Acesulfame Potassium Compositions and Processes for Producing Same ACE, AGT, TST CA1 49/4885CA2 43/4885HTT 1956/4885
US-20210221779-A1 Acesulfame Potassium Compositions and Processes for Producing Same ACE, AGT, TST CA1 49/4885CA2 43/4885HTT 1956/4885
US-11724994-B2 Acesulfame potassium compositions and processes for producing same AGT, ACE, TST CA1 57/4885CA2 42/4885HTT 1866/4885
US-20230322698-A1 Acesulfame Potassium Compositions and Processes for Producing Same AGT, ACE, HCN4 CA1 25/4885CA2 50/4885HTT 779/4885
US-20180079733-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME ACE, AGT, TST CA1 49/4885CA2 43/4885HTT 1956/4885
US-20180079736-A1 ACESULFAME POTASSIUM COMPOSITIONS AND PROCESSES FOR PRODUCING SAME AGT, ACE, HCN4 CA1 25/4885CA2 50/4885HTT 779/4885
US-11724993-B2 Acesulfame potassium compositions and processes for producing same ACE, AGT, TST CA1 49/4885CA2 43/4885HTT 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.