Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649897 | 0.88 | KMT2A (0.61) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL289044 | 0.85 | MAPT (0.74) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL475351 | 0.85 | MAPT (0.74) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL21059260 | 0.83 | MAPT (0.70) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL27744048 | 0.83 | KMT2A (0.54) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL1640627 | 0.82 | MAPT (0.68) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL17503190 | 0.82 | MAPT (0.72) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL626831 | 0.81 | MAPT (0.72) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL28780405 | 0.81 | MAPT (0.72) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL23723484 | 0.81 | MAPT (0.76) | MAPTKDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927695-B2 | Protein-based assays for screening of the IgE-receptor interaction | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-01-06 | — | — | US | disclosed |
| US-20110281365-A1 | PROTEIN-BASED ASSAYS FOR SCREENING OF THE IGE-RECEPTOR INTERACTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |