Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | TACR1 | P25103 | 2/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358032 | 0.88 | MAPT (0.58) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL289044 | 0.87 | MAPT (0.74) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL475351 | 0.87 | MAPT (0.74) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL21059260 | 0.85 | MAPT (0.70) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL27744048 | 0.85 | KMT2A (0.54) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL1640627 | 0.84 | MAPT (0.68) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL17503190 | 0.84 | MAPT (0.72) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL28780405 | 0.83 | MAPT (0.72) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL626831 | 0.83 | MAPT (0.72) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL23723484 | 0.83 | MAPT (0.76) | KMT2AMAPTMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683552-B | Tryptamine salicylic acid compound and preparation and application thereof | 兰州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-113683552-A | Tryptamine salicylic acid compound and preparation and application thereof | 兰州大学 | 2021-11-23 | — | — | CN | disclosed |