Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13582980 | 0.93 | S1PR2 (0.38) | SMN1; SMN2KMT2AMEN1NPC1POLB | |
| SCHEMBL13583320 | 0.93 | UTS2R (0.41) | SMN1; SMN2KMT2AMEN1NPC1POLB | |
| SCHEMBL13822597 | 0.91 | KMT2A (0.41) | SMN1; SMN2KMT2AMEN1KCNA5 | |
| SCHEMBL13822309 | 0.87 | THRB (0.46) | SMN1; SMN2KMT2AMEN1NPC1POLB | |
| SCHEMBL2330698 | 0.87 | CA2 (0.42) | POLBKDRKCNA5HTT | |
| SCHEMBL13822430 | 0.86 | MEN1 (0.43) | KMT2AMEN1NPC1POLBKCNA5 | |
| SCHEMBL13583688 | 0.86 | HPGD (0.47) | SMN1; SMN2KMT2AMEN1NPC1POLB | |
| SCHEMBL13822277 | 0.85 | MEN1 (0.40) | KMT2AMEN1KCNA5 | |
| SCHEMBL13583598 | 0.85 | LMNA (0.46) | SMN1; SMN2POLBHTTTAS1R3TAS1R1 | |
| SCHEMBL13583061 | 0.85 | KDM4E (0.48) | SMN1; SMN2KMT2AMEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524686-B1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | POLA CHEM IND INC (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-9066914-B2 | Prophylactic or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-06-30 | — | — | US | disclosed |
| EP-2524686-A1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | Pola Chemical Industries Inc. (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, NQO1 | SMN1; SMN2 1368/4885KMT2A 1659/4885MEN1 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.